SCOPe 2.05: Structural Classification of Proteins

PDB entry 2nxi

View 2nxi on RCSB PDB site
Description: Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase.
Class: transferase
Keywords: kdo, kdo8p, kdo8ps, pep, a5p, transferase
Deposited on 2006-11-17, released 2007-07-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.207
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxia_
Chain 'B':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxib_
Chain 'C':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxic_
Chain 'D':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxid_
Chain 'E':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxie_
Chain 'F':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxif_
Chain 'G':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxig_
Chain 'H':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxih_
Chain 'I':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxii_
Chain 'J':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxij_
Chain 'K':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxik_
Chain 'L':
Compound: 2-dehydro-3-deoxyphosphooctonate aldolase
Species: Aquifex aeolicus [TaxId:63363]
Gene: kdsA
Database cross-references and differences (RAF-indexed):
- Uniprot O66496 (Start-262)
  - engineered (8-9)
Domains in SCOPe 2.05: d2nxil_
Heterogens: PO4, PEP, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2nxiA (A:)
ekflviagmnaieseelllkvgeeikrlsekfkevefvfkssfdkanrssihsfrghgle
ygvkalrkvkeefglkittdiheswqaepvaevadiiqipaflcrqtdlllaaaktgrav
nvkkgqflapwdtknvveklkfggakeiyltergttfgynnlvvdfrslpimkqwakviy
dathsvqlpgglgdksggmrefifpliraavavgcdgvfmethpepekalsdastqlpls
qlegiieaileirevaskyyeti