Lineage for d2nxic_ (2nxi C:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1815292Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 1821671Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 1822562Family c.1.10.4: Class I DAHP synthetase [51599] (3 proteins)
  6. 1822639Protein 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) [51602] (4 species)
  7. 1822640Species Aquifex aeolicus [TaxId:63363] [63922] (32 PDB entries)
  8. 1822725Domain d2nxic_: 2nxi C: [166429]
    automated match to d1fwna_
    complexed with pep, po4

Details for d2nxic_

PDB Entry: 2nxi (more details), 2.3 Å

PDB Description: structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase.
PDB Compounds: (C:) 2-dehydro-3-deoxyphosphooctonate aldolase

SCOPe Domain Sequences for d2nxic_:

Sequence, based on SEQRES records: (download)

>d2nxic_ c.1.10.4 (C:) 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) {Aquifex aeolicus [TaxId: 63363]}
kflviagmnaieseelllkvgeeikrlsekfkevefvfkssfdkanrssihsfrghgley
gvkalrkvkeefglkittdiheswqaepvaevadiiqipaflcrqtdlllaaaktgravn
vkkgqflapwdtknvveklkfggakeiyltergttfgynnlvvdfrslpimkqwakviyd
athsvqlpgglgdksggmrefifpliraavavgcdgvfmethpepekalsdastqlplsq
legiieaileirevaskyyeti

Sequence, based on observed residues (ATOM records): (download)

>d2nxic_ c.1.10.4 (C:) 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) {Aquifex aeolicus [TaxId: 63363]}
kflviagmnaieseelllkvgeeikrlsekfkevefvfkssfdkanrssihsfrghgley
gvkalrkvkeefglkittdiheswqaepvaevadiiqipaflcrqtdlllaaaktgravn
vkkgqflapwdtknvveklkfggakeiyltergttfgynnlvvdfrslpimkqwakviyd
athsvqlpggggmrefifpliraavavgcdgvfmethpepekalsdastqlplsqlegii
eaileirevaskyyeti

SCOPe Domain Coordinates for d2nxic_:

Click to download the PDB-style file with coordinates for d2nxic_.
(The format of our PDB-style files is described here.)

Timeline for d2nxic_: