PDB entry 2nx5

View 2nx5 on RCSB PDB site
Description: Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A
Class: immune system
Keywords: TCR-pMHC, immune complex, IMMUNE SYSTEM
Deposited on 2006-11-16, released 2007-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.272
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hla-b35
  Species: Homo sapiens [TaxId:9606]
  Gene: B-3501
  Database cross-references and differences (RAF-indexed):
  • Uniprot O19626 (0-275)
  Domains in SCOPe 2.08: d2nx5a1, d2nx5a2
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.08: d2nx5b_
• Chain 'C':
  Compound: EBV peptide, EPLPQGQLTAY
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-10)
• Chain 'D':
  Compound: ELS4 TCR alpha chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-187)
• Chain 'E':
  Compound: ELS4 TCR beta chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-242)
• Chain 'F':
  Compound: hla-b35
  Species: Homo sapiens [TaxId:9606]
  Gene: B-3501
  Database cross-references and differences (RAF-indexed):
  • Uniprot O19626 (0-275)
  Domains in SCOPe 2.08: d2nx5f1, d2nx5f2
• Chain 'G':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.08: d2nx5g_
• Chain 'H':
  Compound: EBV peptide, EPLPQGQLTAY
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-10)
• Chain 'I':
  Compound: ELS4 TCR alpha chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-187)
• Chain 'J':
  Compound: ELS4 TCR beta chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-242)
• Chain 'K':
  Compound: hla-b35
  Species: Homo sapiens [TaxId:9606]
  Gene: B-3501
  Database cross-references and differences (RAF-indexed):
  • Uniprot O19626 (0-275)
  Domains in SCOPe 2.08: d2nx5k1, d2nx5k2
• Chain 'L':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.08: d2nx5l_
• Chain 'M':
  Compound: EBV peptide, EPLPQGQLTAY
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-10)
• Chain 'N':
  Compound: ELS4 TCR alpha chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-187)
• Chain 'P':
  Compound: ELS4 TCR beta chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-242)
• Chain 'Q':
  Compound: hla-b35
  Species: Homo sapiens [TaxId:9606]
  Gene: B-3501
  Database cross-references and differences (RAF-indexed):
  • Uniprot O19626 (0-275)
  Domains in SCOPe 2.08: d2nx5q1, d2nx5q2
• Chain 'R':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61769 (0-98)
  Domains in SCOPe 2.08: d2nx5r_
• Chain 'S':
  Compound: EBV peptide, EPLPQGQLTAY
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-10)
• Chain 'T':
  Compound: ELS4 TCR alpha chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-187)
• Chain 'U':
  Compound: ELS4 TCR beta chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2NX5 (0-242)
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5A (A:)
  gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
  drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
  kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
  radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
  fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5B (B:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5F (F:)
  gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
  drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
  kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
  radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
  fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
  

  
  
• Chain 'G':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5G (G:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  No sequence available.
  
  
• Chain 'K':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5K (K:)
  gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
  drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
  kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
  radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
  fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
  

  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5L (L:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'M':
  No sequence available.
  
  
• Chain 'N':
  No sequence available.
  
  
• Chain 'P':
  No sequence available.
  
  
• Chain 'Q':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5Q (Q:)
  gshsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeyw
  drntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydg
  kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcvewlrrylengketlq
  radppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
  fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
  

  
  
• Chain 'R':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2nx5R (R:)
  iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
  sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'S':
  No sequence available.
  
  
• Chain 'T':
  No sequence available.
  
  
• Chain 'U':
  No sequence available.