PDB entry 2nw8

View 2nw8 on RCSB PDB site
Description: Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and tryptophan. Northeast Structural Genomics Target XcR13.
Class: oxidoreductase
Keywords: all alpha-helical protein, Structural Genomics, PSI-2, Protein Structure Initiative, Northeast Structural Genomics Consortium, NESG, OXIDOREDUCTASE
Deposited on 2006-11-14, released 2006-12-19
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.171
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris [TaxId:340]
    Gene: XCC0432
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2nw8a_
  • Chain 'B':
    Compound: Tryptophan 2,3-dioxygenase
    Species: Xanthomonas campestris [TaxId:340]
    Gene: XCC0432
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2nw8b_
  • Heterogens: MN, TRP, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nw8A (A:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqhqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkrle
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2nw8A (A:)
egrltyggylrldqllsaqqplsepahhdemlfiiqhqtselwlkllahelraaivhlqr
devwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgfqslqyryiefll
gnknpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqqyqardwtaahva
ddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmrvigfkrgtggss
gvgflqqalaltffpelfdvrtsvgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2nw8B (B:)
mpvdknlrdlepgihtdlegrltyggylrldqllsaqqplsepahhdemlfiiqhqtsel
wlkllahelraaivhlqrdevwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvl
gpssgfqslqyryiefllgnknpqmlqvfaydpagqarlrevleapslyeeflrylarfg
haipqqyqardwtaahvaddtlrpvferiyentdrywreyslcedlvdvetqfqlwrfrh
mrtvmrvigfkrgtggssgvgflqqalaltffpelfdvrtsvgvdnrppqgsadagkrle
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2nw8B (B:)
rltyggylrldqllsaqqplsepahhdemlfiiqhqtselwlkllahelraaivhlqrde
vwqcrkvlarskqvlrqlteqwsvletltpseymgfrdvlgpssgfqslqyryiefllgn
knpqmlqvfaydpagqarlrevleapslyeeflrylarfghaipqqyqardwtaahvadd
tlrpvferiyentdrywreyslcedlvdvetqfqlwrfrhmrtvmrvigfssgvgflqqa
laltffpelfdvrtsvgvdnrppq