PDB entry 2nnj

View 2nnj on RCSB PDB site
Description: CYP2C8dH complexed with felodipine
Class: oxidoreductase,electron transport
Keywords: CYP2C8; Human P450 2C8; monooxygenases; Felodipine; Plendil; inhibitor complex; palmitic acid, OXIDOREDUCTASE,ELECTRON TRANSPORT
Deposited on 2006-10-24, released 2007-10-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: 0.24
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2C8
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2C8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2nnja_
  • Heterogens: SO4, HEM, 225, PLM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nnjA (A:)
makktsskgklppgptplpiignmlqidvkdicksftnfskvygpvftvyfgmnpivvfh
gyeavkealidngeefsgrgnspisqritkglgiissngkrwkeirrfslttlrnfgmgk
rsiedrvqeeahclveelrktkaspcdptfilgcapcnvicsvvfqkrfdykdqnfltlm
krfnenfrilnspwiqvcnnfpllidcfpgthnkvlknvaltrsyirekvkehqasldvn
nprdfidcflikmeqekdnqksefnienlvgtvadlfvagtettsttlryglllllkhpe
vtakvqeeidhvigrhrspcmqdrshmpytdavvheiqrysdlvptgvphavttdtkfrn
ylipkgttimalltsvlhddkefpnpnifdpghfldkngnfkksdyfmpfsagkricage
glarmelflflttilqnfnlksvddlknlnttavtkgivslppsyqicfipvhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2nnjA (A:)
klppgptplpiignmlqidvkdicksftnfskvygpvftvyfgmnpivvfhgyeavkeal
idngeefsgrgnspisqritkglgiissngkrwkeirrfslttlrnfgmgkrsiedrvqe
eahclveelrktkaspcdptfilgcapcnvicsvvfqkrfdykdqnfltlmkrfnenfri
lnspwiqvcnnfpllidcfpgthnkvlknvaltrsyirekvkehqasldvnnprdfidcf
likmeqekdnqksefnienlvgtvadlfvagtettsttlryglllllkhpevtakvqeei
dhvigrhrspcmqdrshmpytdavvheiqrysdlvptgvphavttdtkfrnylipkgtti
malltsvlhddkefpnpnifdpghfldkngnfkksdyfmpfsagkricageglarmelfl
flttilqnfnlksvddlknlnttavtkgivslppsyqicfipv