PDB entry 2lef

View 2lef on RCSB PDB site
Description: lef1 hmg domain (from mouse), complexed with DNA (15bp), nmr, 12 structures
Class: gene regulation/DNA
Keywords: lef1, hmg, tcr-a, transcription factor, DNA binding, DNA bending, complex (hmg domain/DNA), gene regulation/DNA complex
Deposited on 1998-10-13, released 1998-10-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (lymphoid enhancer-binding factor)
    Species: Mus musculus [TaxId:10090]
    Gene: LEF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27782 (0-85)
      • conflict (0)
      • engineered (24)
    Domains in SCOPe 2.07: d2lefa_
  • Chain 'B':
    Compound: DNA (5'-d(*cp*ap*cp*cp*cp*tp*tp*tp*gp*ap*ap*gp*cp*tp*c)-3')
  • Chain 'C':
    Compound: DNA (5'-d(*gp*ap*gp*cp*tp*tp*cp*ap*ap*ap*gp*gp*gp*tp*g)-3')

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2lefA (A:)
mhikkplnafmlymkemranvvaestlkesaainqilgrrwhalsreeqakyyelarker
qlhmqlypgwsardnygkkkkrkrek

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.