PDB entry 2ipf

View 2ipf on RCSB PDB site
Description: Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP+ and epi-testosterone
Class: oxidoreductase
Keywords: 17a-HSD, AKR1C21, AKR, aldo-keto reductase, HSD, hydroxysteroid dehydrogenase, open conformation, epi-testosterone, OXIDOREDUCTASE
Deposited on 2006-10-12, released 2007-06-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-05-16, with a file datestamp of 2012-05-11.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.171
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: (3(17)alpha-hydroxysteroid dehydrogenase)
    Species: Mus musculus [TaxId:10090]
    Gene: Akr1c21
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ipfa_
  • Chain 'B':
    Compound: (3(17)alpha-hydroxysteroid dehydrogenase)
    Species: Mus musculus [TaxId:10090]
    Gene: Akr1c21
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2ipfb_
  • Heterogens: NAP, FFA, BME, EDO, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ipfA (A:)
hcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedhvgeai
rskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypmalkpg
eenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkpglkyk
pvcnqvechpylnqmklldfckskdivlvaygvlgtqryggwvdqnspvlldepvlgsma
kkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldglnrnmry
ipaaifkghpnwpfldey

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ipfB (B:)
hcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedhvgeai
rskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypmalkpg
eenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkpglkyk
pvcnqvechpylnqmklldfckskdivlvaygvlgtqryggwvdqnspvlldepvlgsma
kkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldglnrnmry
ipaaifkghpnwpfldey