PDB entry 2iik

View 2iik on RCSB PDB site
Description: Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
Class: transferase
Keywords: FATTY ACID METABOLISM, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2006-09-28, released 2006-10-10
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.181
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-ketoacyl-CoA thiolase, peroxisomal
    Species: Homo sapiens [TaxId:9606]
    Gene: ACAA1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2iika1, d2iika2
  • Chain 'B':
    Compound: 3-ketoacyl-CoA thiolase, peroxisomal
    Species: Homo sapiens [TaxId:9606]
    Gene: ACAA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09110 (23-416)
      • cloning artifact (14-22)
    Domains in SCOPe 2.04: d2iikb1, d2iikb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2iikA (A:)
mhhhhhhssgvdlgtenlyfqsmapqasaadvvvvhgrrtaicragrggfkdttpdells
avmtavlkdvnlrpeqlgdicvgnvlqpgagaimariaqflsdipetvplstvnrqcssg
lqavasiaggirngsydigmacgvesmsladrgnpgnitsrlmekekardclipmgitse
nvaerfgisrekqdtfalasqqkaaraqskgcfqaeivpvtttvhddkgtkrsitvtqde
girpsttmeglaklkpafkkdgsttagnssqvsdgaaaillarrskaeelglpilgvlrs
yavvgvppdimgigpayaipvalqkagltvsdvdifeineafasqaaycveklrlppekv
nplggavalghplgctgarqvitllnelkrrgkraygvvsmcigtgmgaaavfeypgn

    Sequence, based on observed residues (ATOM records): (download) 
    >2iikA (A:)
asaadvvvvhgrrtaicragrggfkdttpdellsavmtavlkdvnlrpeqlgdicvgnvl
qpgagaimariaqflsdipetvplstvnrqcssglqavasiaggirngsydigmacgves
msladgnitsrlmekekardclipmgitsenvaerfgisrekqdtfalasqqkaaraqsk
gcfqaeivpvtttvhddkgtkrsitvtqdegirpsttmeglaklkpafkkdgsttagnss
qvsdgaaaillarrskaeelglpilgvlrsyavvgvppdimgigpayaipvalqkagltv
sdvdifeineafasqaaycveklrlppekvnplggavalghplgctgarqvitllnelkr
rgkraygvvsmcigtgmgaaavfeyp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2iikB (B:)
mhhhhhhssgvdlgtenlyfqsmapqasaadvvvvhgrrtaicragrggfkdttpdells
avmtavlkdvnlrpeqlgdicvgnvlqpgagaimariaqflsdipetvplstvnrqcssg
lqavasiaggirngsydigmacgvesmsladrgnpgnitsrlmekekardclipmgitse
nvaerfgisrekqdtfalasqqkaaraqskgcfqaeivpvtttvhddkgtkrsitvtqde
girpsttmeglaklkpafkkdgsttagnssqvsdgaaaillarrskaeelglpilgvlrs
yavvgvppdimgigpayaipvalqkagltvsdvdifeineafasqaaycveklrlppekv
nplggavalghplgctgarqvitllnelkrrgkraygvvsmcigtgmgaaavfeypgn

    Sequence, based on observed residues (ATOM records): (download) 
    >2iikB (B:)
tenlyfqsmapqasaadvvvvhgrrtaicragrggfkdttpdellsavmtavlkdvnlrp
eqlgdicvgnvlqpgagaimariaqflsdipetvplstvnrqcssglqavasiaggirng
sydigmacgvesmslapgnitsrlmekekardclipmgitsenvaerfgisrekqdtfal
asqqkaaraqskgcfqaeivpvtttvhddkgtkrsitvtqdegirpsttmeglaklkpaf
kkdgsttagnssqvsdgaaaillarrskaeelglpilgvlrsyavvgvppdimgigpaya
ipvalqkagltvsdvdifeineafasqaaycveklrlppekvnplggavalghplgctga
rqvitllnelkrrgkraygvvsmcigtgmgaaavfeypgn