PDB entry 2i3v

View 2i3v on RCSB PDB site
Description: Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant
Class: membrane protein
Keywords: Ionotropic glutamate receptor ligand binding core S1S2 G725C mutant, MEMBRANE PROTEIN
Deposited on 2006-08-21, released 2006-10-17
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.237
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (117-258)
      • linker (117-118)
    Domains in SCOPe 2.04: d2i3va_
  • Chain 'B':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (117-258)
      • linker (117-118)
    Domains in SCOPe 2.04: d2i3vb_
  • Chain 'C':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (117-258)
      • linker (117-118)
    Domains in SCOPe 2.04: d2i3vc_
  • Chain 'D':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (117-258)
      • linker (117-118)
    Domains in SCOPe 2.04: d2i3vd_
  • Heterogens: ZN, GLU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2i3vA (A:)
nktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyg
ardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpie
saedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvr
kskgkyayllestmneyieqrkpcdtmkvgcnldskgygiatpkgsslgnavnlavlkln
eqglldklknkwwydkgec

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2i3vB (B:)
nktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyg
ardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpie
saedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvr
kskgkyayllestmneyieqrkpcdtmkvgcnldskgygiatpkgsslgnavnlavlkln
eqglldklknkwwydkgec

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2i3vC (C:)
nktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyg
ardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpie
saedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvr
kskgkyayllestmneyieqrkpcdtmkvgcnldskgygiatpkgsslgnavnlavlkln
eqglldklknkwwydkgec

    Sequence, based on observed residues (ATOM records): (download) 
    >2i3vC (C:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvgcnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2i3vD (D:)
nktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyg
ardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpie
saedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvr
kskgkyayllestmneyieqrkpcdtmkvgcnldskgygiatpkgsslgnavnlavlkln
eqglldklknkwwydkgec

    Sequence, based on observed residues (ATOM records): (download) 
    >2i3vD (D:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvgcnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec