PDB entry 2i22

View 2i22 on RCSB PDB site
Description: Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate
Class: isomerase
Keywords: lipopolysaccharide biosynthesis, phosphoheptose isomerase, ISOMERASE
Deposited on 2006-08-15, released 2007-08-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-06-22, with a file datestamp of 2011-06-17.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.207
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoheptose isomerase
    Species: Escherichia coli [TaxId:562]
    Gene: gmhA, lpcA, tfrA, b0222
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2i22a_
  • Chain 'B':
    Compound: Phosphoheptose isomerase
    Species: Escherichia coli [TaxId:562]
    Gene: gmhA, lpcA, tfrA, b0222
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2i22b_
  • Chain 'C':
    Compound: Phosphoheptose isomerase
    Species: Escherichia coli [TaxId:562]
    Gene: gmhA, lpcA, tfrA, b0222
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2i22c_
  • Chain 'D':
    Compound: Phosphoheptose isomerase
    Species: Escherichia coli [TaxId:562]
    Gene: gmhA, lpcA, tfrA, b0222
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2i22d_
  • Heterogens: I22, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2i22A (A:)
mgsshhhhhhssglvprgshmyqdlirnelneaaetlanflkddanihaiqraavllads
fkaggkvlscgnggshcdamhfaeeltgryrenrpgypaiaisdvshiscvgndfgfndi
fsryveavgregdvllgistsgnsanvikaiaaarekgmkvitltgkdggkmagtadiei
rvphfgyadriqeihikvihiliqliekemvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2i22A (A:)
myqdlirnelneaaetlanflkddanihaiqraavlladsfkaggkvlscgnggshcdam
hfaeeltgryrenrpgypaiaisdndifsryveavgregdvllgistsgnsanvikaiaa
arekgmkvitltgkdggkmagtadieirvphfgyadriqeihikvihiliqliekemvk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2i22B (B:)
mgsshhhhhhssglvprgshmyqdlirnelneaaetlanflkddanihaiqraavllads
fkaggkvlscgnggshcdamhfaeeltgryrenrpgypaiaisdvshiscvgndfgfndi
fsryveavgregdvllgistsgnsanvikaiaaarekgmkvitltgkdggkmagtadiei
rvphfgyadriqeihikvihiliqliekemvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2i22B (B:)
myqdlirnelneaaetlanflkddanihaiqraavlladsfkaggkvlscgnggshcdam
hfaeeltgryrenrpgypaiaisndifsryveavgregdvllgistsgnsanvikaiaaa
rekgmkvitltgkdggkmagtadieirvphfgyadriqeihikvihiliqliekemvk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2i22C (C:)
mgsshhhhhhssglvprgshmyqdlirnelneaaetlanflkddanihaiqraavllads
fkaggkvlscgnggshcdamhfaeeltgryrenrpgypaiaisdvshiscvgndfgfndi
fsryveavgregdvllgistsgnsanvikaiaaarekgmkvitltgkdggkmagtadiei
rvphfgyadriqeihikvihiliqliekemvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2i22C (C:)
myqdlirnelneaaetlanflkddanihaiqraavlladsfkaggkvlscgnggshcdam
hfaeeltgryrenrpgypaiaisndifsryveavgregdvllgistsgnsanvikaiaaa
rekgmkvitltgkdggkmagtadieirvphfgyadriqeihikvihiliqliekemvk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2i22D (D:)
mgsshhhhhhssglvprgshmyqdlirnelneaaetlanflkddanihaiqraavllads
fkaggkvlscgnggshcdamhfaeeltgryrenrpgypaiaisdvshiscvgndfgfndi
fsryveavgregdvllgistsgnsanvikaiaaarekgmkvitltgkdggkmagtadiei
rvphfgyadriqeihikvihiliqliekemvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2i22D (D:)
myqdlirnelneaaetlanflkddanihaiqraavlladsfkaggkvlscgnggshcdam
hfaeeltgryrenrpgypaiaisndifsryveavgregdvllgistsgnsanvikaiaaa
rekgmkvitltgkdggkmagtadieirvphfgyadriqeihikvihiliqliekemvk