PDB entry 2hc0

View 2hc0 on RCSB PDB site
Description: Structure of HIV protease 6X mutant in complex with AB-2.
Class: hydrolase
Keywords: HIV, protease, mutant, aspartyl, HYDROLASE
Deposited on 2006-06-14, released 2007-06-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: 0.161
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367
    • engineered (6)
    • engineered (23)
    • engineered (45)
    • engineered (52)
    • engineered (62)
    • engineered (76)
    • engineered (81)
  Domains in SCOPe 2.06: d2hc0a_
• Chain 'B':
  Compound: Protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (6)
    • engineered (23)
    • engineered (45)
    • engineered (52)
    • engineered (62)
    • engineered (76)
    • engineered (81)
  Domains in SCOPe 2.06: d2hc0b_
• Heterogens: BR, AB2, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2hc0A (A:)
  pqitlwkrplvtikiggqlkealidtgaddtvleemnlpgrwkpkiiggigglikvrqyd
  qipieicghkaigtvligptpaniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2hc0B (B:)
  pqitlwkrplvtikiggqlkealidtgaddtvleemnlpgrwkpkiiggigglikvrqyd
  qipieicghkaigtvligptpaniigrnlltqigctlnf