PDB entry 2gmv

View 2gmv on RCSB PDB site
Description: PEPCK complex with a GTP-competitive inhibitor
Class: Lyase
Keywords: gluconeogenesis, xanthine, inhibitor
Deposited on 2006-04-07, released 2007-05-29
The last revision prior to the SCOP 1.75 freeze date was dated 2007-08-21, with a file datestamp of 2007-08-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.217
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoenolpyruvate carboxykinase, cytosolic
    Species: HOMO SAPIENS
    Gene: PCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35558 (Start-624)
      • variant (186)
      • variant (269)
      • variant (588)
      • variant (599)
    Domains in SCOP 1.75: d2gmva1, d2gmva2
  • Chain 'B':
    Compound: Phosphoenolpyruvate carboxykinase, cytosolic
    Species: HOMO SAPIENS
    Gene: PCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35558 (Start-624)
      • variant (186)
      • variant (269)
      • variant (588)
      • variant (599)
    Domains in SCOP 1.75: d2gmvb1, d2gmvb2
  • Heterogens: MN, PEP, UN8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gmvA (A:)
gelmppqlqnglnlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrll
gqmeeegilrrlkkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwm
seedfekafnarfpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmg
tpvlealgdgefvkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgygg
nsllgkkcfalrmasrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammn
pslpgwkvecvgddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntif
tnvaetsdggvywegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiid
aawespegvpiegiifggrrpagvplvyealswqhgvfvgaamrseataaaehkgkiimh
dpfamrpffgynfgkylahwlsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvl
ewmfnridgkastkltpigyipkedalnlkglghinmmelfsiskefwdkevediekylv
dqvnadlpceiereilalkqrisqm

    Sequence, based on observed residues (ATOM records): (download) 
    >2gmvA (A:)
nlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrllgqmeeegilrrl
kkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwmseedfekafnar
fpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmgtpvlealgdgef
vkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgyggnsllgkkcfalr
masrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvg
ddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvy
wegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpie
giifggrrpagvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahw
lsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgtkltpigyipk
edalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqris
qm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2gmvB (B:)
gelmppqlqnglnlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrll
gqmeeegilrrlkkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwm
seedfekafnarfpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmg
tpvlealgdgefvkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgygg
nsllgkkcfalrmasrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammn
pslpgwkvecvgddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntif
tnvaetsdggvywegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiid
aawespegvpiegiifggrrpagvplvyealswqhgvfvgaamrseataaaehkgkiimh
dpfamrpffgynfgkylahwlsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvl
ewmfnridgkastkltpigyipkedalnlkglghinmmelfsiskefwdkevediekylv
dqvnadlpceiereilalkqrisqm

    Sequence, based on observed residues (ATOM records): (download) 
    >2gmvB (B:)
nlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrllgqmeeegilrrl
kkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwmseedfekafnar
fpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmgtpvlealgdgef
vkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgyggnsllgkkcfalr
masrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvg
ddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvy
wegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpie
giifggrrpagvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahw
lsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgtkltpigyipk
edalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqris
qm