PDB entry 2gk6

View 2gk6 on RCSB PDB site
Description: Structural and Functional insights into the human Upf1 helicase core
Class: hydrolase
Keywords: Upf1, helicase, NMD, HYDROLASE
Deposited on 2006-03-31, released 2007-01-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.237
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Regulator of nonsense transcripts 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92900 (4-End)
      • cloning artifact (2-3)
    Domains in SCOPe 2.07: d2gk6a1, d2gk6a2, d2gk6a3, d2gk6a4
  • Chain 'B':
    Compound: Regulator of nonsense transcripts 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92900 (4-End)
      • cloning artifact (2-3)
    Domains in SCOPe 2.07: d2gk6b1, d2gk6b2, d2gk6b3, d2gk6b4
  • Heterogens: MG, PO4, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gk6A (A:)
plgsryedayqyqnifgplvkleadydkklkesqtqdnitvrwdlglnkkriayftlpkt
dsdmrlmqgdeiclrykgdlaplwkgighvikvpdnygdeiaielrssvgapvevthnfq
vdfvwkstsfdrmqsalktfavdetsvsgyiyhkllghevedviikcqlpkrftaqglpd
lnhsqvyavktvlqrplsliqgppgtgktvtsativyhlarqgngpvlvcapsniavdql
tekihqtglkvvrlcaksreaidspvsflalhnqirnmdsmpelqklqqlkdetgelssa
dekryralkrtaerellmnadvicctcvgagdprlakmqfrsilidestqatepecmvpv
vlgakqlilvgdhcqlgpvvmckkaakaglsqslferlvvlgirpirlqvqyrmhpalsa
fpsnifyegslqngvtaadrvkkgfdfqwpqpdkpmffyvtqgqeeiassgtsylnrtea
anvekittkllkagakpdqigiitpyegqrsylvqymqfsgslhtklyqeveiasvdafq
grekdfiilscvranehqgigflndprrlnvaltrarygviivgnpkalskqplwnhlln
yykeqkvlvegplnnlreslmqfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2gk6A (A:)
gsryedayqyqnifgplvkleadydkklkesqtqdnitvrwdlglnkkriayftlplmqg
deiclrykgdlaplwkgighvikvpdnygdeiaielrssvgapvevthnfqvdfvwksts
fdrmqsalktfavdetsvsgyiyhkllghevedviikcqlpkrftaqglpdlnhsqvyav
ktvlqrplsliqgppgtgktvtsativyhlarqgngpvlvcapsniavdqltekihqtgl
kvvrlcaksreaidspvsflalhnqirnmdsmpelqklqqlkdlssadekryralkrtae
rellmnadvicctcvgagdprlakmqfrsilidestqatepecmvpvvlgakqlilvgdh
cqlgpvvmckkaakaglsqslferlvvlgirpirlqvqyrmhpalsafpsnifyegslqn
gvtaadrvkkgfdfqwpqpdkpmffyvtqgqeeiassgtsylnrteaanvekittkllka
gakpdqigiitpyegqrsylvqymqfsgslhtklyqeveiasvdafqgrekdfiilscvr
igflndprrlnvaltrarygviivgnpkalskqplwnhllnyykeqkvlvegplnnlres
lm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2gk6B (B:)
plgsryedayqyqnifgplvkleadydkklkesqtqdnitvrwdlglnkkriayftlpkt
dsdmrlmqgdeiclrykgdlaplwkgighvikvpdnygdeiaielrssvgapvevthnfq
vdfvwkstsfdrmqsalktfavdetsvsgyiyhkllghevedviikcqlpkrftaqglpd
lnhsqvyavktvlqrplsliqgppgtgktvtsativyhlarqgngpvlvcapsniavdql
tekihqtglkvvrlcaksreaidspvsflalhnqirnmdsmpelqklqqlkdetgelssa
dekryralkrtaerellmnadvicctcvgagdprlakmqfrsilidestqatepecmvpv
vlgakqlilvgdhcqlgpvvmckkaakaglsqslferlvvlgirpirlqvqyrmhpalsa
fpsnifyegslqngvtaadrvkkgfdfqwpqpdkpmffyvtqgqeeiassgtsylnrtea
anvekittkllkagakpdqigiitpyegqrsylvqymqfsgslhtklyqeveiasvdafq
grekdfiilscvranehqgigflndprrlnvaltrarygviivgnpkalskqplwnhlln
yykeqkvlvegplnnlreslmqfs

    Sequence, based on observed residues (ATOM records): (download) 
    >2gk6B (B:)
gsryedayqyqnifgplvkleadydkklkesqtqdnitvrwdlglnkkriayftlplmqg
deiclrykgdlaplwkgighvikvpdnygdeiaielrssvgapvevthnfqvdfvwksts
fdrmqsalktfavdetsvsgyiyhkllghevedviikcqlpkrftaqglpdlnhsqvyav
ktvlqrplsliqgppgtgktvtsativyhlarqgngpvlvcapsniavdqltekihqtgl
kvvrlcaksreaidspvsflalhnqirnmdsmpelqklqqlkdlssadekryralkrtae
rellmnadvicctcvgagdprlakmqfrsilidestqatepecmvpvvlgakqlilvgdh
cqlgpvvmckkaakaglsqslferlvvlgirpirlqvqyrmhpalsafpsnifyegslqn
gvtaadrvkkgfdfqwpqpdkpmffyvtqgqeeiassgtsylnrteaanvekittkllka
gakpdqigiitpyegqrsylvqymqfsgslhtklyqeveiasvdafqgrekdfiilscvr
igflndprrlnvaltrarygviivgnpkalskqplwnhllnyykeqkvlvegplnnlres
lm