SCOPe 2.06: Structural Classification of Proteins

PDB entry 2flo

View 2flo on RCSB PDB site
Description: Crystal structure of exopolyphosphatase (PPX) from E. coli O157:H7
Class: hydrolase
Keywords: exopolyphosphatase, PPX/GPPA, metaphosphatase, Structural Genomics, Bacterial Structural Genomics, Montreal-Kingston Bacterial Structural Genomics Initiative, BSGI, HYDROLASE
Deposited on 2006-01-06, released 2006-06-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.205
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: exopolyphosphatase
Species: Escherichia coli [TaxId:83334]
Gene: ppx
Database cross-references and differences (RAF-indexed):
- Uniprot P0AFL8
  - modified residue (35)
  - modified residue (45)
  - modified residue (66)
  - modified residue (72)
  - modified residue (137)
  - modified residue (177)
  - modified residue (202)
  - modified residue (224)
  - modified residue (238)
  - modified residue (240)
  - modified residue (315)
  - modified residue (351)
  - modified residue (353)
  - modified residue (378)
  - modified residue (414-415)
Domains in SCOPe 2.06: d2floa1, d2floa2, d2floa3
Chain 'B':
Compound: exopolyphosphatase
Species: Escherichia coli [TaxId:83334]
Gene: ppx
Database cross-references and differences (RAF-indexed):
- Uniprot P0AFL8
  - modified residue (35)
  - modified residue (45)
  - modified residue (66)
  - modified residue (72)
  - modified residue (137)
  - modified residue (177)
  - modified residue (202)
  - modified residue (224)
  - modified residue (238)
  - modified residue (240)
  - modified residue (315)
  - modified residue (351)
  - modified residue (353)
  - modified residue (378)
  - modified residue (414-415)
Domains in SCOPe 2.06: d2flob1, d2flob2, d2flob3
Chain 'C':
Compound: exopolyphosphatase
Species: Escherichia coli [TaxId:83334]
Gene: ppx
Database cross-references and differences (RAF-indexed):
- Uniprot P0AFL8
  - modified residue (35)
  - modified residue (45)
  - modified residue (66)
  - modified residue (72)
  - modified residue (137)
  - modified residue (177)
  - modified residue (202)
  - modified residue (224)
  - modified residue (238)
  - modified residue (240)
  - modified residue (315)
  - modified residue (351)
  - modified residue (353)
  - modified residue (378)
  - modified residue (414-415)
Domains in SCOPe 2.06: d2floc1, d2floc2, d2floc3
Chain 'D':
Compound: exopolyphosphatase
Species: Escherichia coli [TaxId:83334]
Gene: ppx
Database cross-references and differences (RAF-indexed):
- Uniprot P0AFL8
  - modified residue (35)
  - modified residue (45)
  - modified residue (66)
  - modified residue (72)
  - modified residue (137)
  - modified residue (177)
  - modified residue (202)
  - modified residue (224)
  - modified residue (238)
  - modified residue (240)
  - modified residue (315)
  - modified residue (351)
  - modified residue (353)
  - modified residue (378)
  - modified residue (414-415)
Domains in SCOPe 2.06: d2flod1, d2flod2, d2flod3
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2floA (A:)
mgsshhhhhhgspihdksprpqefaavdlgsnsfhmviarvvdgamqiigrlkqrvhlad
glgpdnmlseeamtrglnclslfaerlqgfspasvcivgthtlrqalnatdflkraekvi
pypieiisgneearlifmgvehtqpekgrklvidigggstelvigenfepilvesrrmgc
vsfaqlyfpggvinkenfqrarmaaaqkletltwqfriqgwnvamgasgtikaahevlme
mgekdgiitperleklvkevlrhrnfaslslpglseerktvfvpglailcgvfdalaire
lrlsdgalregvlyemegrfrhqdvrsrtasslanqyhidseqarrvldttmqmyeqwre
qqpklahpqleallrwaamlhevglninhsglhrhsayilqnsdlpgfnqeqqlmmatlv
ryhrkaiklddlprftlfkkkqflpliqllrlgvllnnqrqatttpptltlitddshwtl
rfphdwfsqnalvlldlekeqeywegvagwrlkieeestpeiaa

Sequence, based on observed residues (ATOM records): (download)

>2floA (A:)
qefaavdlgsnsfhmviarvvdgamqiigrlkqrvhladglgpdnmlseeamtrglncls
lfaerlqgfspasvcivgthtlrqalnatdflkraekvipypieiisgneearlifmgve
htqpekgrklvidigggstelvigenfepilvesrrmgcvsfaqlyfpggvinkenfqra
rmaaaqkletltwqfriqgwnvamgasgtikaahevlmemgekdgiitperleklvkevl
rhrnfaslslpglseerktvfvpglailcgvfdalairelrlsdgalregvlyemegrfr
hqdvrsrtasslanqyhidseqarrvldttmqmyeqwreqqpklahpqleallrwaamlh
evglninhsglhrhsayilqnsdlpgfnqeqqlmmatlvryhrkaiklddlprftlfkkk
qflpliqllrlgvllnnqrqatttpptltlitddshwtlrfphdwfsqnalvlldlekeq
eywegvagwrlkieee

Chain 'B':
Sequence, based on SEQRES records: (download)

>2floB (B:)
mgsshhhhhhgspihdksprpqefaavdlgsnsfhmviarvvdgamqiigrlkqrvhlad
glgpdnmlseeamtrglnclslfaerlqgfspasvcivgthtlrqalnatdflkraekvi
pypieiisgneearlifmgvehtqpekgrklvidigggstelvigenfepilvesrrmgc
vsfaqlyfpggvinkenfqrarmaaaqkletltwqfriqgwnvamgasgtikaahevlme
mgekdgiitperleklvkevlrhrnfaslslpglseerktvfvpglailcgvfdalaire
lrlsdgalregvlyemegrfrhqdvrsrtasslanqyhidseqarrvldttmqmyeqwre
qqpklahpqleallrwaamlhevglninhsglhrhsayilqnsdlpgfnqeqqlmmatlv
ryhrkaiklddlprftlfkkkqflpliqllrlgvllnnqrqatttpptltlitddshwtl
rfphdwfsqnalvlldlekeqeywegvagwrlkieeestpeiaa

Sequence, based on observed residues (ATOM records): (download)

>2floB (B:)
efaavdlgsnsfhmviarvvdgamqiigrlkqrvhladglgpdnmlseeamtrglnclsl
faerlqgfspasvcivgthtlrqalnatdflkraekvipypieiisgneearlifmgveh
tqpekgrklvidigggstelvigenfepilvesrrmgcvsfaqlyfpggvinkenfqrar
maaaqkletltwqfriqgwnvamgasgtikaahevlmemgekdgiitperleklvkevlr
hrnfaslslpglseerktvfvpglailcgvfdalairelrlsdgalregvlyemegrfrh
qdvrsrtasslanqyhidseqarrvldttmqmyeqwreqqpklahpqleallrwaamlhe
vglninhsglhrhsayilqnsdlpgfnqeqqlmmatlvryhrkaiklddlprftlfkkkq
flpliqllrlgvllnnqrqatttpptltlitddshwtlrfphdwfsqnalvlldlekeqe
ywegvagwrlkieee

Chain 'C':
Sequence, based on SEQRES records: (download)

>2floC (C:)
mgsshhhhhhgspihdksprpqefaavdlgsnsfhmviarvvdgamqiigrlkqrvhlad
glgpdnmlseeamtrglnclslfaerlqgfspasvcivgthtlrqalnatdflkraekvi
pypieiisgneearlifmgvehtqpekgrklvidigggstelvigenfepilvesrrmgc
vsfaqlyfpggvinkenfqrarmaaaqkletltwqfriqgwnvamgasgtikaahevlme
mgekdgiitperleklvkevlrhrnfaslslpglseerktvfvpglailcgvfdalaire
lrlsdgalregvlyemegrfrhqdvrsrtasslanqyhidseqarrvldttmqmyeqwre
qqpklahpqleallrwaamlhevglninhsglhrhsayilqnsdlpgfnqeqqlmmatlv
ryhrkaiklddlprftlfkkkqflpliqllrlgvllnnqrqatttpptltlitddshwtl
rfphdwfsqnalvlldlekeqeywegvagwrlkieeestpeiaa

Sequence, based on observed residues (ATOM records): (download)

>2floC (C:)
qefaavdlgsnsfhmviarvvdgamqiigrlkqrvhladglgpdnmlseeamtrglncls
lfaerlqgfspasvcivgthtlrqalnatdflkraekvipypieiisgneearlifmgve
htqpekgrklvidigggstelvigenfepilvesrrmgcvsfaqlyfpggvinkenfqra
rmaaaqkletltwqfriqgwnvamgasgtikaahevlmemgekdgiitperleklvkevl
rhrnfaslslpglseerktvfvpglailcgvfdalairelrlsdgalregvlyemegrfr
hqdvrsrtasslanqyhidseqarrvldttmqmyeqwreqqpklahpqleallrwaamlh
evglninhsglhrhsayilqnsdlpgfnqeqqlmmatlvryhrkaiklddlprftlfkkk
qflpliqllrlgvllnnqrqatttpptltlitddshwtlrfphdwfsqnalvlldlekeq
eywegvagwrlkieee

Chain 'D':
Sequence, based on SEQRES records: (download)

>2floD (D:)
mgsshhhhhhgspihdksprpqefaavdlgsnsfhmviarvvdgamqiigrlkqrvhlad
glgpdnmlseeamtrglnclslfaerlqgfspasvcivgthtlrqalnatdflkraekvi
pypieiisgneearlifmgvehtqpekgrklvidigggstelvigenfepilvesrrmgc
vsfaqlyfpggvinkenfqrarmaaaqkletltwqfriqgwnvamgasgtikaahevlme
mgekdgiitperleklvkevlrhrnfaslslpglseerktvfvpglailcgvfdalaire
lrlsdgalregvlyemegrfrhqdvrsrtasslanqyhidseqarrvldttmqmyeqwre
qqpklahpqleallrwaamlhevglninhsglhrhsayilqnsdlpgfnqeqqlmmatlv
ryhrkaiklddlprftlfkkkqflpliqllrlgvllnnqrqatttpptltlitddshwtl
rfphdwfsqnalvlldlekeqeywegvagwrlkieeestpeiaa

Sequence, based on observed residues (ATOM records): (download)

>2floD (D:)
qefaavdlgsnsfhmviarvvdgamqiigrlkqrvhladglgpdnmlseeamtrglncls
lfaerlqgfspasvcivgthtlrqalnatdflkraekvipypieiisgneearlifmgve
htqpekgrklvidigggstelvigenfepilvesrrmgcvsfaqlyfpggvinkenfqra
rmaaaqkletltwqfriqgwnvamgasgtikaahevlmemgekdgiitperleklvkevl
rhrnfaslslpglseerktvfvpglailcgvfdalairelrlsdgalregvlyemegrfr
hqdvrsrtasslanqyhidseqarrvldttmqmyeqwreqqpklahpqleallrwaamlh
evglninhsglhrhsayilqnsdlpgfnqeqqlmmatlvryhrkaiklddlprftlfkkk
qflpliqllrlgvllnnqrqatttpptltlitddshwtlrfphdwfsqnalvlldlekeq
eywegvagwrlkieee