PDB entry 2ebc

View 2ebc on RCSB PDB site
Description: Mechanism underlying the critical contribution of a switch II residue in a heterotrimeric G-protein alpha subunit during C. elegans asymmetric cell division
Class: signaling protein
Keywords: G-protein, alpha subunit, GTPase, guanine nucleotide, mutant, SIGNALING PROTEIN
Deposited on 2007-02-08, released 2008-02-19
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-09-01, with a file datestamp of 2009-08-28.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: 0.229
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Guanine nucleotide-binding protein G(i), alpha-1 subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63096 (Start-353)
      • engineered (201)
    Domains in SCOPe 2.01: d2ebca1, d2ebca2
  • Heterogens: GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ebcA (A:)
mgctlsaedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheag
yseeeckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmt
aelagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvk
ttgivethftfkdlhfkmfdvdgqrserkkwihcfegvtaiifcvalsdydlvlaedeem
nrmhesmklfdsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaa
ayiqcqfedlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >2ebcA (A:)
dkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagyseeeckq
ykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmtaelagvik
rlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvkttgiveth
ftfkdlhfkmfdvdgqrseihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfds
icnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnk
rkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf