PDB entry 2e09

View 2e09 on RCSB PDB site
Description: Structure of mutant tryptophan synthase alpha-subunit (E74A) from a hyperthermophile, Pyrococcus furiosus
Class: Lyase
Keywords: tryptophan synthase alpha-subunit, hyperthermophile, pyrococcus furiosus, x-ray analysis, stability, calorimetry, Lyase, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2006-10-02, released 2007-08-28
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.203
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tryptophan synthase alpha chain
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: trpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8U094 (0-247)
      • engineered (73)
    Domains in SCOPe 2.02: d2e09a_
  • Chain 'B':
    Compound: tryptophan synthase alpha chain
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: trpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8U094 (0-247)
      • engineered (73)
    Domains in SCOPe 2.02: d2e09b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2e09A (A:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkafrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygttgareeipktay
dllrrakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkk
kveellgi

    Sequence, based on observed residues (ATOM records): (download) 
    >2e09A (A:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkafrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygteeipktaydllr
rakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkkkvee
llgi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2e09B (B:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkafrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygttgareeipktay
dllrrakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkk
kveellgi

    Sequence, based on observed residues (ATOM records): (download) 
    >2e09B (B:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkafrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygtteeipktaydll
rrakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkkkve
ellgi