PDB entry 2d4v

View 2d4v on RCSB PDB site
Description: Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans
Class: oxidoreductase
Keywords: alpha and beta protein, Isocitrate/Isopropylmalate dehydrogenase-like fold, OXIDOREDUCTASE
Deposited on 2005-10-24, released 2006-11-14
The last revision prior to the SCOPe 2.02 freeze date was dated 2008-07-01, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.181
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: isocitrate dehydrogenase
    Species: Acidithiobacillus thiooxidans [TaxId:930]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2d4va_
  • Chain 'B':
    Compound: isocitrate dehydrogenase
    Species: Acidithiobacillus thiooxidans [TaxId:930]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2d4vb_
  • Chain 'C':
    Compound: isocitrate dehydrogenase
    Species: Acidithiobacillus thiooxidans [TaxId:930]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2d4vc_
  • Chain 'D':
    Compound: isocitrate dehydrogenase
    Species: Acidithiobacillus thiooxidans [TaxId:930]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2d4vd_
  • Heterogens: FLC, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2d4vA (A:)
mtthiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggq
rqiawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrq
dldlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflr
eemgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkftegg
frdwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflq
qillrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiag
qgkanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstte
ftaalirrf

    Sequence, based on observed residues (ATOM records): (download) 
    >2d4vA (A:)
thiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggqrq
iawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrqdl
dlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflree
mgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkfteggfr
dwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflqqi
llrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiagqg
kanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstteft
aalirrf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2d4vB (B:)
mtthiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggq
rqiawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrq
dldlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflr
eemgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkftegg
frdwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflq
qillrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiag
qgkanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstte
ftaalirrf

    Sequence, based on observed residues (ATOM records): (download) 
    >2d4vB (B:)
thiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggqrq
iawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrqdl
dlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflree
mgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkfteggfr
dwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflqqi
llrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiagqg
kanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstteft
aalirrf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2d4vC (C:)
mtthiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggq
rqiawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrq
dldlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflr
eemgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkftegg
frdwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflq
qillrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiag
qgkanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstte
ftaalirrf

    Sequence, based on observed residues (ATOM records): (download) 
    >2d4vC (C:)
thiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggqrq
iawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrqdl
dlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflree
mgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkfteggfr
dwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflqqi
llrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiagqg
kanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstteft
aalirrf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2d4vD (D:)
mtthiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggq
rqiawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrq
dldlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflr
eemgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkftegg
frdwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflq
qillrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiag
qgkanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstte
ftaalirrf

    Sequence, based on observed residues (ATOM records): (download) 
    >2d4vD (D:)
thiqkpatgspltllngvlqvpdqpiipfiegdgigcdvtpamrsvvdaavakvyggqrq
iawmelfagqkavqlygegqylpdetmaaireykvaikgpletpvgggirslnvamrqdl
dlyvclrpvryfegtpspmrhpekvdmvifrensediyagiewpagspeaekiirflree
mgvtkirfpdssaigikpvstegserlirrtiqyalehgkpsvslvhkgnimkfteggfr
dwgyalaerefagrvftwrqkaaiskaegkaagqkaeqqaiadgkliikdviadnflqqi
llrpedysvvatlnlngdyvsdalaaevggigmapganlsdthaifeathgtapdiagqg
kanpsslilsavmmlehlgwgeaaqaivaamnatiaagevtgdlaalrgdvpalstteft
aalirrf