PDB entry 2cnq

View 2cnq on RCSB PDB site
Description: atomic resolution structure of saicar-synthase from saccharomyces cerevisiae complexed with ADP, aicar, succinate
Class: ligase
Keywords: ligase, phosphoribosylaminoimidazolesuccinocarboxamide (saicar) syn ligase, synthetase, acetylation, ATP-binding protein, purine biosynthesis
Deposited on 2006-05-23, released 2006-06-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1 Å
R-factor: 0.116
AEROSPACI score: 1.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphoribosylaminoimidazole-succinocarboxamide synthase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2CNQ
      • conflict see remark 9 (183)
    • Uniprot P27616 (0-End)
    Domains in SCOPe 2.07: d2cnqa_
  • Heterogens: ADP, AMZ, AMP, SIN, MG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cnqA (A:)
sitkteldgilplvargkvrdiyevdagtllfvatdrisaydvimensipekgilltkls
efwfkflsndvrnhlvdiapgktifdylpaklsepkyktqledrsllvhkhklipleviv
rgyitgsawkeyvktgtvhglkqpqglkesqefpepiftpstkaeqgehdenispaqaae
lvgedlsrrvaelavklyskckdyakekgiiiadtkfefgidektneiilvdevltpdss
rfwngasykvgesqdsydkqflrdwltanklngvngvkmpqdivdrtrakyieayetltg
skwsh

    Sequence, based on observed residues (ATOM records): (download) 
    >2cnqA (A:)
sitkteldgilplvargkvrdiyevdagtllfvatdrisaydvimensipekgilltkls
efwfkflsndvrnhlvdiapgktifdylpaklsepkyktqledrsllvhkhklipleviv
rgyitgsawkeyvktgtvhglkqpqglkesqefpepiftpstkaehdenispaqaaelvg
edlsrrvaelavklyskckdyakekgiiiadtkfefgidektneiilvdevltpdssrfw
ngasykvgesqdsydkqflrdwltanklngvngvkmpqdivdrtrakyieayetltgskw
s