PDB entry 2cn1

View 2cn1 on RCSB PDB site
Description: crystal structure of human cytosolic 5'-nucleotidase III (nt5c3)(casp target)
Class: hydrolase
Keywords: pyrimidine 5-prime- nucleotidase 1, alternative splicing, nucleotide metabolism, pyrimidine 5-prime nucleotidase deficiency, uridine 5-prime monophosphate hydrolase 1, cytosolic III, disease mutation, nucleotide-binding, p5n1, umph1, 5-prime, hydrolase, nucleotidase
Deposited on 2006-05-17, released 2006-06-12
The last revision prior to the SCOP 1.75 freeze date was dated 2006-06-12, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.67 Å
R-factor: 0.196
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytosolic 5'-nucleotidase III
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • PDB 2CN1
    • Uniprot Q9H0P0 (19-291)
    Domains in SCOP 1.75: d2cn1a1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cn1A (A:)
mgsshhhhhhssglvprgsnptrveeiicglikggaaklqiitdfdmtlsrfsykgkrcp
tchniidncklvtdecrkkllqlkekyyaievdpvltveekypymvewytkshgllvqqa
lpkaklkeivaesdvmlkegyenffdklqqhsipvfifsagigdvleevirqagvyhpnv
kvvsnfmdfdetgvlkgfkgelihvfnkhdgalrnteyfnqlkdnsniillgdsqgdlrm
adgvanvehilkigylndrvdellekymdsydivlvqdeslevansilqkil

    Sequence, based on observed residues (ATOM records): (download) 
    >2cn1A (A:)
nptrveeiicglikggaaklqiitdfdmtlsrfsykgkrcptchniidncklvtdecrkk
llqlkekyyaievdpvltveekypymvewytkshgllvqqalpkaklkeivaesdvmlke
gyenffdklqqhsipvfifsagigdvleevirqagvyhpnvkvvsnfmdfdetgvlkgfk
gelihvfnkhdgalrnteyfnqlkdnsniillgdsqgdlrmadgvanvehilkigylndr
vdellekymdsydivlvqdeslevansilqkil