PDB entry 2cgn
View 2cgn on RCSB PDB site
Description: FACTOR INHIBITING HIF-1 ALPHA with succinate
Class: oxidoreductase
Keywords: 2-oxoglutarate, acetylation, activator, oxidoreductase, alternative splicing, asparaginyl hydroxylase, DNA-binding, dsbh, fi, hif, hydroxylation, hypoxia, nuclear protein, oxygenase, phosphorylation, polymorphism, s-nitrosylation, transcription, transcription activator/inhibitor, transcription regulation
Deposited on
2006-03-09, released
2006-12-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-21, with a file datestamp of
2018-02-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hypoxia-inducible factor 1 alpha inhibitor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2cgna_ - Heterogens: FE, SIN, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2cgnA (A:)
maataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelienee
pvvltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnr
eemkfhefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwg
qltsnllligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqs
qvdfdnpdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykga
ptpkrieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn
Sequence, based on observed residues (ATOM records): (download)
>2cgnA (A:)
ataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepv
vltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfnreemkfhefv
eklqdiqqreerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligm
egnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyer
fpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplk
ahqkvaimrniekmlgealgnpqevgpllntmikgryn