Lineage for d2cgna_ (2cgn A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2070014Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2070786Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2070961Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein)
  6. 2070962Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species)
  7. 2070963Species Human (Homo sapiens) [TaxId:9606] [82196] (34 PDB entries)
  8. 2070978Domain d2cgna_: 2cgn A: [130426]
    automated match to d1iz3a_
    complexed with fe, sin, so4

Details for d2cgna_

PDB Entry: 2cgn (more details), 2.4 Å

PDB Description: factor inhibiting hif-1 alpha with succinate
PDB Compounds: (A:) hypoxia-inducible factor 1 alpha inhibitor

SCOPe Domain Sequences for d2cgna_:

Sequence, based on SEQRES records: (download)

>d2cgna_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
ataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepv
vltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnree
mkfhefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgql
tsnllligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqv
dfdnpdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgapt
pkrieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn

Sequence, based on observed residues (ATOM records): (download)

>d2cgna_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
ataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepv
vltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfnreemkfhefv
eklqdiqqreerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligm
egnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyer
fpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplk
ahqkvaimrniekmlgealgnpqevgpllntmikgryn

SCOPe Domain Coordinates for d2cgna_:

Click to download the PDB-style file with coordinates for d2cgna_.
(The format of our PDB-style files is described here.)

Timeline for d2cgna_: