PDB entry 2cg5

View 2cg5 on RCSB PDB site
Description: structure of aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Class: transferase/hydrolase
Keywords: transferase-hydrolase complex, transferase-hydrolase (complex), fatty acid biosynthesis, phosphopantetheine transferase, fasn, acp, coenzyme a, transferase, hydrolase, lipid synthesis, lyase, complex
Deposited on 2006-02-27, released 2006-03-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.195
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: l-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2CG5 (Start-22)
    • Uniprot Q9NRN7 (23-End)
  • Chain 'B':
    Compound: fatty acid synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2CG5
      • engineered mutation (39)
    • Uniprot P49327
    Domains in SCOPe 2.06: d2cg5b_
  • Heterogens: COA, MG, NI, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2cg5B (B:)
gtrdrdsqrdlveavahilgirdlaavnldssladlgldalmsvevrqtlerelnlvlsv
revrqltlrklqelsskadeaselacptpke

    Sequence, based on observed residues (ATOM records): (download) 
    >2cg5B (B:)
qrdlveavahilgirdlaavnldssladlgldalmsvevrqtlerelnlvlsvrevrqlt
lrklqelsska