PDB entry 2c5a

View 2c5a on RCSB PDB site
Description: GDP-mannose-3', 5' -epimerase (arabidopsis thaliana), y174f, with GDP-beta-l-galactose bound in the active site
Class: isomerase
Keywords: 3' 5'-epimerase, short chain dehydratase/reductase, GDP-mannose, GDP-gulose, GDP-galactose, keto intermediate, vitamin c, sdr, ascorbate biosynthesis, isomerase, nad
Deposited on 2005-10-26, released 2005-11-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.105
AEROSPACI score: 0.75 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GDP-mannose-3', 5'-epimerase
    Species: Arabidopsis thaliana [TaxId:3702]
    Database cross-references and differences (RAF-indexed):
    • PDB 2C5A
      • engineered mutation (175)
    • Uniprot Q93VR3
    Domains in SCOPe 2.06: d2c5aa1
  • Chain 'B':
    Compound: GDP-mannose-3', 5'-epimerase
    Species: Arabidopsis thaliana [TaxId:3702]
    Database cross-references and differences (RAF-indexed):
    • PDB 2C5A
      • engineered mutation (175)
    • Uniprot Q93VR3
    Domains in SCOPe 2.06: d2c5ab_
  • Heterogens: GDC, NAD, FMT, BTB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c5aA (A:)
gamgttngtdygaytykelereqywpsenlkisitgaggfiashiarrlkheghyviasd
wkknehmtedmfcdefhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimyn
ntmisfnmieaaringikrffyassaciypefkqlettnvslkesdawpaepqdafglek
lateelckhynkdfgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgd
glqtrsftfidecvegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhip
gpegvrgrnsdnnlikeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskv
vgtqapvqlgslraadgke

    Sequence, based on observed residues (ATOM records): (download) 
    >2c5aA (A:)
tykelereqywpsenlkisitgaggfiashiarrlkheghyviasdwkknehmtedmfcd
efhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimynntmisfnmieaari
ngikrffyassaciypefkqlettnvslkesdawpaepqdafgleklateelckhynkdf
giecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgdglqtrsftfidecv
egvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhipgpegvrgrnsdnnl
ikeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskvvgtqapvqlgslra
adgk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c5aB (B:)
gamgttngtdygaytykelereqywpsenlkisitgaggfiashiarrlkheghyviasd
wkknehmtedmfcdefhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimyn
ntmisfnmieaaringikrffyassaciypefkqlettnvslkesdawpaepqdafglek
lateelckhynkdfgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgd
glqtrsftfidecvegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhip
gpegvrgrnsdnnlikeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskv
vgtqapvqlgslraadgke

    Sequence, based on observed residues (ATOM records): (download) 
    >2c5aB (B:)
ytykelereqywpsenlkisitgaggfiashiarrlkheghyviasdwkknehmtedmfc
defhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimynntmisfnmieaar
ingikrffyassaciypefkqlettnvslkesdawpaepqdafgleklateelckhynkd
fgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgdglqtrsftfidec
vegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhipgpegvrgrnsdnn
likeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskvvgtqapvqlgslr
a