PDB entry 2bkz

View 2bkz on RCSB PDB site
Description: structure of cdk2-cyclin a with pha-404611
Class: transferase/complex
Keywords: protein kinase, transferase, serine/threonine-protein kinase, phosphorylation, cell division, cyclin, ATP-binding, cell cycle, mitosis, polymorphism
Deposited on 2005-02-23, released 2006-03-08
The last revision prior to the SCOP 1.73 freeze date was dated 2006-03-08, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.23
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2bkza1
  • Chain 'B':
    Compound: cyclin a2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2bkzb1, d2bkzb2
  • Chain 'C':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2bkzc1
  • Chain 'D':
    Compound: cyclin a2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2bkzd1, d2bkzd2
  • Heterogens: SO4, SBC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bkzA (A:)
gplvdmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisll
kelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqgl
afchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeill
gckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpd
ykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvph
lrlerphrd

    Sequence, based on observed residues (ATOM records): (download) 
    >2bkzA (A:)
plvdmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllk
elnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqgla
fchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillg
ckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdy
kpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
rl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bkzB (B:)
gplgsnevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeykl
qnetlhlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyt
kkqvlrmehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpy
lkylpsviagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqq
sirekyknskyhgvsllnppetlnl

    Sequence, based on observed residues (ATOM records): (download) 
    >2bkzB (B:)
pdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhla
vnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrme
hlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsvi
agaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekykn
skyhgvsllnppetlnl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2bkzC (C:)
gplvdmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisll
kelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqgl
afchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeill
gckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpd
ykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvph
lrlerphrd

    Sequence, based on observed residues (ATOM records): (download) 
    >2bkzC (C:)
dmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2bkzD (D:)
gplgsnevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeykl
qnetlhlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyt
kkqvlrmehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpy
lkylpsviagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqq
sirekyknskyhgvsllnppetlnl

    Sequence, based on observed residues (ATOM records): (download) 
    >2bkzD (D:)
yhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhlavn
yidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrmehl
vlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsviag
aafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyknsk
yhgvsllnppetlnl