PDB entry 2b3y

View 2b3y on RCSB PDB site
Description: Structure of a monoclinic crystal form of human cytosolic aconitase (IRP1)
Class: lyase
Keywords: IRP1 IRE-IRP1 aconitase activity, LYASE
Deposited on 2005-09-22, released 2006-01-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.213
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Iron-responsive element binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2b3ya1, d2b3ya2
  • Chain 'B':
    Compound: Iron-responsive element binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2b3yb1, d2b3yb2
  • Heterogens: ACT, SF4, GOL, FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b3yA (A:)
snpfahlaepldpvqpgkkffnlnkledsrygrlpfsirvlleaairncdeflvkkqdie
nilhwnvtqhknievpfkparvilqdftgvpavvdfaamrdavkklggdpekinpvcpad
lvidhsiqvdfnrradslqknqdlefernrerfeflkwgsqafhnmriippgsgiihqvn
leylarvvfdqdgyyypdslvgtdshttmidglgilgwgvggieaeavmlgqpismvlpq
vigyrlmgkphplvtstdivltitkhlrqvgvvgkfveffgpgvaqlsiadratianmcp
eygataaffpvdevsitylvqtgrdeeklkyikkylqavgmfrdfndpsqdpdftqvvel
dlktvvpccsgpkrpqdkvavsdmkkdfesclgakqgfkgfqvapehhndhktfiydnte
ftlahgsvviaaitsctntsnpsvmlgagllakkavdaglnvmpyiktslspgsgvvtyy
lqesgvmpylsqlgfdvvgygcmtcignsgplpepvveaitqgdlvavgvlsgnrnfegr
vhpntranylaspplviayaiagtiridfekeplgvnakgqqvflkdiwptrdeiqaver
qyvipgmfkevyqkietvneswnalatpsdklffwnskstyiksppffenltldlqppks
ivdayvllnlgdsvttdhispagniarnspaaryltnrgltprefnsygsrrgndavmar
gtfanirllnrflnkqapqtihlpsgeildvfdaaeryqqaglplivlagkeygagssrd
waakgpfllgikavlaesyerihrsnlvgmgvipleylpgenadalgltgqerytiiipe
nlkpqmkvqvkldtgktfqavmrfdtdveltyflnggilnymirkmak

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b3yB (B:)
snpfahlaepldpvqpgkkffnlnkledsrygrlpfsirvlleaairncdeflvkkqdie
nilhwnvtqhknievpfkparvilqdftgvpavvdfaamrdavkklggdpekinpvcpad
lvidhsiqvdfnrradslqknqdlefernrerfeflkwgsqafhnmriippgsgiihqvn
leylarvvfdqdgyyypdslvgtdshttmidglgilgwgvggieaeavmlgqpismvlpq
vigyrlmgkphplvtstdivltitkhlrqvgvvgkfveffgpgvaqlsiadratianmcp
eygataaffpvdevsitylvqtgrdeeklkyikkylqavgmfrdfndpsqdpdftqvvel
dlktvvpccsgpkrpqdkvavsdmkkdfesclgakqgfkgfqvapehhndhktfiydnte
ftlahgsvviaaitsctntsnpsvmlgagllakkavdaglnvmpyiktslspgsgvvtyy
lqesgvmpylsqlgfdvvgygcmtcignsgplpepvveaitqgdlvavgvlsgnrnfegr
vhpntranylaspplviayaiagtiridfekeplgvnakgqqvflkdiwptrdeiqaver
qyvipgmfkevyqkietvneswnalatpsdklffwnskstyiksppffenltldlqppks
ivdayvllnlgdsvttdhispagniarnspaaryltnrgltprefnsygsrrgndavmar
gtfanirllnrflnkqapqtihlpsgeildvfdaaeryqqaglplivlagkeygagssrd
waakgpfllgikavlaesyerihrsnlvgmgvipleylpgenadalgltgqerytiiipe
nlkpqmkvqvkldtgktfqavmrfdtdveltyflnggilnymirkmak