PDB entry 2awg

View 2awg on RCSB PDB site
Description: Structure of the PPIase domain of the Human FK506-binding protein 8
Class: signaling protein inhibitor
Keywords: FKBP-type, PPIase, Bcl-2 INHIBITOR, SHH SIGNALLING ANTAGONIST, Structural Genomics Consortium, SGC, SIGNALING PROTEIN INHIBITOR
Deposited on 2005-09-01, released 2005-09-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.169
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: 38 kDa FK-506 binding protein
  Species: Homo sapiens [TaxId:9606]
  Gene: FKBP8, FKBP38
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q14318 (2-117)
    • cloning artifact (0-1)
  Domains in SCOPe 2.06: d2awga1, d2awga2
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2awgA (A:)
  gspeewldilgngllrkktlvpgppgssrpvkgqvvtvhlqtslengtrvqeepelvftl
  gdcdviqaldlsvplmdvgetamvtadskycygpqgrspyipphaalclevtlktavd