PDB entry 2aew
View 2aew on RCSB PDB site
Description: A model for growth hormone receptor activation based on subunit rotation within a receptor dimer
Class: hormone/growth factor
Keywords: HORMONE/GROWTH FACTOR, mechanism
Deposited on
2005-07-24, released
2005-11-01
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.257
AEROSPACI score: 0.2
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: growth hormone receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2aewa1, d2aewa2 - Chain 'B':
Compound: growth hormone receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2aewb1, d2aewb2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2aewA (A:)
sskepkftkcrsperetfschwtdevhhgtknlgpiqlfytrrntqewtqewkecpdyvs
agenscyfnssftsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltg
ihadiqvrweaprnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkey
evrvrskqrnsgnygefsevlyvtl
Sequence, based on observed residues (ATOM records): (download)
>2aewA (A:)
sskepkftkcrsperetfschwtdevnlgpiqlfytrrnqewkecpdyvsagenscyfns
sftsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrwe
aprnamvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnyge
fsevlyvtl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2aewB (B:)
sskepkftkcrsperetfschwtdevhhgtknlgpiqlfytrrntqewtqewkecpdyvs
agenscyfnssftsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltg
ihadiqvrweaprnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkey
evrvrskqrnsgnygefsevlyvtl
Sequence, based on observed residues (ATOM records): (download)
>2aewB (B:)
kepkftkcrsperetfschwtdgpiqlfytrrqewkecpdyvsagenscyfnssftsiwi
pycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadi
qkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygef
sevlyvtl