PDB entry 1zxb

View 1zxb on RCSB PDB site
Description: Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2005-06-07, released 2006-06-13
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.68 Å
R-factor: 0.236
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: enoyl-acyl carrier reductase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: PfENR
    Database cross-references and differences (RAF-indexed):
    • GB NP_703811 (0-End)
    Domains in SCOPe 2.02: d1zxba_
  • Chain 'B':
    Compound: enoyl-acyl carrier reductase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: PfENR
    Database cross-references and differences (RAF-indexed):
    • GB NP_703811 (0-End)
    Domains in SCOPe 2.02: d1zxbb_
  • Heterogens: NAD, TN3

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zxbA (A:)
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntnq
nknrnshdvhnimnnsgekeekknsasqnytfidyaieysekyaplrqkllstdigsvas
fllsresraitgqtiyvdnglnimflpddiyrnene

    Sequence, based on observed residues (ATOM records): (download) 
    >1zxbA (A:)
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainkytfidyaieys
ekyaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpdd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zxbB (B:)
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntnq
nknrnshdvhnimnnsgekeekknsasqnytfidyaieysekyaplrqkllstdigsvas
fllsresraitgqtiyvdnglnimflpddiyrnene

    Sequence, based on observed residues (ATOM records): (download) 
    >1zxbB (B:)
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainkytfidyaieys
ekyaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpdd