PDB entry 1zua

View 1zua on RCSB PDB site
Description: Crystal Structure Of AKR1B10 Complexed With NADP+ And Tolrestat
Class: Oxidoreductase
Keywords: alpha-beta barrel, aldo-keto reductase, Oxidoreductase
Deposited on 2005-05-30, released 2006-11-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-05-26, with a file datestamp of 2009-05-22.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: 0.131
AEROSPACI score: 0.82 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: Aldo-keto reductase family 1 member B10
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B10
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60218 (1-316)
      • expression tag (0)
      • engineered (313)
    Domains in SCOPe 2.04: d1zuax_
  • Heterogens: NAP, TOL, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1zuaX (X:)
hmatfvelstkakmpivglgtwksplgkvkeavkvaidagyrhidcayvyqnehevgeai
qekiqekavkredlfivsklwptfferplvrkafektlkdlklsyldvylihwpqgfksg
ddlfpkddkgnaiggkatfldaweameelvdeglvkalgvsnfshfqiekllnkpglkyk
pvtnqvechpyltqekliqychskgitvtaysplgspdrpwakpedpslledpkikeiaa
khkktaaqvlirfhiqrnvivipksvtpariveniqvfdfklsdeematilsfnrnwrac
nvlqsshledypfnaey