PDB entry 1zpt

View 1zpt on RCSB PDB site
Description: Escherichia coli Methylenetetrahydrofolate Reductase (reduced) complexed with NADH, pH 7.25
Class: oxidoreductase
Keywords: tim barrel, flavin, reductase, nadh, oxidoreductase
Deposited on 2005-05-17, released 2005-08-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-11-06, with a file datestamp of 2013-11-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.219
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1zpta_
  • Chain 'B':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1zptb_
  • Chain 'C':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1zptc_
  • Heterogens: SO4, FAD, NAI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zptA (A:)
msffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zptA (A:)
hasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtythsi
ikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgmyasdlvtllkeva
dfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylrfrdrcvsagi
dveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvganiamdmvki
lsregvkdfhfytlnraemsyaichtlgvrp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zptB (B:)
msffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zptB (B:)
ffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtyga
nsgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgdle
myasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdve
sylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetr
klvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1zptC (C:)
msffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zptC (C:)
qinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtygansgerdrthsiikgikdrt
gleaaphltcidatpdelrtiardywnngirhivalrgdlmyasdlvtllkevadfdisv
aaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylrfrdrcvsagidveiip
gilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvganiamdmvkilsregv
kdfhfytlnraemsyaichtlgvrp