PDB entry 1zkx

View 1zkx on RCSB PDB site
Description: Crystal structure of Glu158Ala/Thr159Ala/Asn160Ala- a triple mutant of Clostridium botulinum neurotoxin E catalytic domain
Class: hydrolase
Keywords: botulinum neurotoxin E, catalytic domain, light chain, Glu158Ala/Thr159Ala/Asn160Ala mutant, HYDROLASE
Deposited on 2005-05-04, released 2005-07-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: 0.208
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: botulinum neurotoxin type E
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00496 (0-End)
      • engineered (157-159)
    Domains in SCOPe 2.06: d1zkxa_
  • Chain 'B':
    Compound: botulinum neurotoxin type E
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00496 (0-End)
      • engineered (157-159)
    Domains in SCOPe 2.06: d1zkxb_
  • Heterogens: ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zkxA (A:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfaaassnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpli
tnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykd
vfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkls
nllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkgi

    Sequence, based on observed residues (ATOM records): (download) 
    >1zkxA (A:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfaaassnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitgtnieef
ltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykdvfeakygldkd
asgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfklsnllndsiynis
egyninnlkvnfrgqnanlnpriitpitgrglvkkiirfc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zkxB (B:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfhpptsl
kngdssyydpnylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpd
nqfhigdasaveikfsngsqdillpnviimgaepdlfaaassnislrnnympsnhgfgsi
aivtfspeysfrfndnsmnefiqdpaltlmhelihslhglygakgittkytitqkqnpli
tnirgtnieefltfggtdlniitsaqsndiytnlladykkiasklskvqvsnpllnpykd
vfeakygldkdasgiysvninkfndifkklysftefdlatkfqvkcrqtyigqykyfkls
nllndsiynisegyninnlkvnfrgqnanlnpriitpitgrglvkkiirfcknivsvkgi

    Sequence, based on observed residues (ATOM records): (download) 
    >1zkxB (B:)
pkinsfnyndpvndrtilyikpggcqefyksfnimkniwiipernvigttpqdfsyydpn
ylqsdeekdrflkivtkifnrinnnlsggilleelskanpylgndntpdnqfhigdasav
eikfsngsqdillpnviimgaepdlfaaassnislrnnympsnhgfgsiaivtfspeysf
rfndnsmnefiqdpaltlmhelihslhglygakgittkytitgtnieefltfggtdlnii
tsaqsndiytnlladykkiasklskvqvsnpllnpykdvfeakygldkdasgiysvnink
fndifkklysftefdlatkfqvkcrqtyigqykyfklsnllndsiynisegyninnlkvn
frgqnanlnpriitpitgrglvkkiir