PDB entry 1xrr

View 1xrr on RCSB PDB site
Description: Crystal structure of active site F1-mutant E245Q soaked with peptide Pro-Pro
Class: hydrolase
Keywords: alpha-beta hydrolase, caged active site, substrate recognition, hydrogen bonded network, diproline
Deposited on 2004-10-15, released 2005-07-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.236
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: proline iminopeptidase
    Species: Thermoplasma acidophilum [TaxId:2303]
    Gene: TA0830
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96084 (Start-292)
      • engineered (244)
    Domains in SCOPe 2.06: d1xrra_
  • Heterogens: PRO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xrrA (A:)
mdqecienyakvngiyiyyklckapeekaklmtmhggpgmshdyllslrdmtkegitvlf
ydqfgcgrseepdqskftidygveeaealrsklfgnekvflmgssyggalalayavkyqd
hlkglivsgglssvpltvkemnrlidelpakyrdaikkygssgsyenpeyqeavnyfyhq
hllrsedwppevlksleyaerrnvyrimngpneftitgtikdwditdkisaikiptlitv
geydqvtpnvarvihekiagselhvfrdcshltmwedregynkllsdfilkhl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xrrA (A:)
ecienyakvngiyiyyklckapeekaklmtmhggpgmshdyllslrdmtkegitvlfydq
fgcgrseepdqskftidygveeaealrsklfgnekvflmgssyggalalayavkyqdhlk
glivsgglssvpltvkemnrlidelpakyrdaikkygssgsyenpeyqeavnyfyhqhll
rsedwppevlksleyaerrnvyrimngpneftitgtikdwditdkisaikiptlitvgey
dqvtpnvarvihekiagselhvfrdcshltmwedregynkllsdfilkhl