PDB entry 1xrl

View 1xrl on RCSB PDB site
Description: Crystal structure of active site F1-mutant Y205F complex with inhibitor PCK
Class: hydrolase
Keywords: alpha-beta hydrolase, caged active site, substrate recognition, hydrogen bonded network, chloromethyl ketone inhibitor
Deposited on 2004-10-15, released 2005-07-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-09-15, with a file datestamp of 2009-09-11.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.241
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: proline iminopeptidase
    Species: Thermoplasma acidophilum [TaxId:2303]
    Gene: TA0830
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96084 (Start-292)
      • engineered (204)
    Domains in SCOPe 2.06: d1xrla_
  • Heterogens: PHK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xrlA (A:)
mdqecienyakvngiyiyyklckapeekaklmtmhggpgmshdyllslrdmtkegitvlf
ydqfgcgrseepdqskftidygveeaealrsklfgnekvflmgssyggalalayavkyqd
hlkglivsgglssvpltvkemnrlidelpakyrdaikkygssgsyenpeyqeavnyfyhq
hllrsedwppevlksleyaerrnvfrimngpneftitgtikdwditdkisaikiptlitv
geydevtpnvarvihekiagselhvfrdcshltmwedregynkllsdfilkhl

    Sequence, based on observed residues (ATOM records): (download) 
    >1xrlA (A:)
ecienyakvngiyiyyklckapeekaklmtmhggpgmshdyllslrdmtkegitvlfydq
fgcgrseepdqskftidygveeaealrsklfgnekvflmgssyggalalayavkyqdhlk
glivsgglssvpltvkemnrlidelpakyrdaikkygssgsyenpeyqeavnyfyhqhll
rsedwppevlksleyaerrnvfrimngpneftitgtikdwditdkisaikiptlitvgey
devtpnvarvihekiagselhvfrdcshltmwedregynkllsdfilkhl