PDB entry 1wa5

View 1wa5 on RCSB PDB site
Description: Structure of the Cse1:Imp-alpha:RanGTP complex
Class: transport protein
Keywords: Cse1, Importin-alpha, RanGTP, nuclear transport, TRANSPORT PROTEIN
Deposited on 2004-10-23, released 2004-12-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-04, with a file datestamp of 2020-10-30.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding nuclear protein ran
    Species: Canis lupus familiaris [TaxId:9615]
    Gene: RAN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1wa5a_
  • Chain 'B':
    Compound: SRP1 isoform 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SRP1, GI526_G0004888
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1wa5b_
  • Chain 'C':
    Compound: importin alpha re-exporter
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CSE1, YGL238W, HRC135
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1wa5c_
  • Heterogens: GTP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1wa5A (A:)
maaqgepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpik
fnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlc
gnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlef

    Sequence, based on observed residues (ATOM records): (download) 
    >1wa5A (A:)
pqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlef

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1wa5B (B:)
mdngtdsstskfvpeyrrtnfknkgrfsadelrrrrdtqqvelrkakrdealakrrnfip
ptdgadsdeedessvsadqqfysqlqqelpqmtqqlnsddmqeqlsatvkfrqilsqehr
ppidvviqagvvprlvefmrenqpemlqleaawaltniasgtsaqtkvvvdadavplfiq
llytgsvevkeqaiwalgnvagdstdyrdyvlqcnamepilglfnsnkpslirtatwtls
nlcrgkkpqpdwsvvsqalptlakliysmdtetlvdacwaisylsdgpqeaiqavidvri
pkrlvellshestlvqtpalravgnivtgndlqtqvvinagvlpalrlllsspkenikke
acwtisnitagnteqiqavidanlipplvkllevaeyktkkeacwaisnassgglqrpdi
irylvsqgcikplcdlleiadnriievtldalenilkmgeadkearglninenadfieka
ggmekifncqqnendkiyekaykiietyfgeeedavdetmapqnagntfg

    Sequence, based on observed residues (ATOM records): (download) 
    >1wa5B (B:)
kfvpeyrrtnelrrrrdtqqvelrkakrdealakrrnfqelpqmtqqlnsddmqeqlsat
vkfrqilsqrppidvviqagvvprlvefmrenqpemlqleaawaltniasgtsaqtkvvv
dadavplfiqllytgsvevkeqaiwalgnvagdstdyrdyvlqcnamepilglfnsnkps
lirtatwtlsnlcrgkkpqpdwsvvsqalptlakliysmdtetlvdacwaisylsdgpqe
aiqavidvripkrlvellshestlvqtpalravgnivtgndlqtqvvinagvlpalrlll
sspkenikkeacwtisnitagnteqiqavidanlipplvkllevaeyktkkeacwaisna
ssgglqrpdiirylvsqgcikplcdlleiadnriievtldalenilkmgeadkearglni
nenadfiekaggmekifncqqnendkiyekaykiietyfgeeedav

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1wa5C (C:)
msdletvakflaesviastaktsernlrqletqdgfgltllhviastnlplstrlagalf
fknfikrkwvdengnhllpannvelikkeivplmislpnnlqvqigeaissiadsdfpdr
wptllsdlasrlsnddmvtnkgvltvahsifkrwrplfrsdelfleiklvldvftapfln
llktvdeqitanennkaslnilfdvllvliklyydfncqdipeffedniqvgmgifhkyl
sysnplledpdetehasvlikvkssiqelvqlyttryedvfgpminefiqitwnlltsis
nqpkydilvskslsfltavtripkyfeifnnesamnniteqiilpnvtlreedvelfedd
pieyirrdlegsdtdtrrractdflkelkeknevlvtniflahmkgfvdqymsdpsknwk
fkdlyiylftalaingnitnagvsstnnllnvvdfftkeiapdltsnniphiilrvdaik
yiytfrnqltkaqlielmpilatflqtdeyvvytyaaitiekiltiresntspafifhke
disnsteillknlialilkhgsspeklaeneflmrsifrvlqtsedsiqplfpqllaqfi
eivtimaknpsnprfthytfesigailnytqrqnlpllvdsmmptfltvfsediqefipy
vfqiiafvveqsatipesikplaqpllapnvwelkgnipavtrllksfiktdssifpdlv
pvlgifqrliaskayevhgfdllehimllidmnrlrpyikqiavlllqrlqnskteryvk
kltvffglisnklgsdflihfidevqdglfqqiwgnfiittlptignlldrkialigvln
mvingqffqskyptlisstmnsiietassqsianlkndyvdldnleeistfgshfsklvs
isekpfdplpeidvnngvrlyvaealnkynaisgntflntilpqltqenqvklnqllvgn

    Sequence, based on observed residues (ATOM records): (download) 
    >1wa5C (C:)
msdletvakflaesviastaktsernlrqletqdgfgltllhviastnlplstrlagalf
fknfikrkwvdengnhllpannvelikkeivplmislpnnlqvqigeaissiadsdfpdr
wptllsdlasrlsnddmvtnkgvltvahsifkrwrplfrsdelfleiklvldvftapfln
llktvdeqitanennkaslnilfdvllvliklyydfncqdipeffedniqvgmgifhkyl
sysnplledpdetehasvlikvkssiqelvqlyttryedvfgpminefiqitwnlltsis
nqpkydilvskslsfltavtripkyfeifnnesamnniteqiilpnvtlreedvelfedd
pieyirrdlegtdtrrractdflkelkeknevlvtniflahmkgfvdqymsdpsknwkfk
dlyiylftalaingnitnagvsstnnllnvvdfftkeiapdltsnniphiilrvdaikyi
ytfrnqltkaqlielmpilatflqtdeyvvytyaaitiekiltiresntspafifhkedi
snsteillknlialilkhgsspeklaeneflmrsifrvlqtsedsiqplfpqllaqfiei
vtimaknpsnprfthytfesigailnytqrqnlpllvdsmmptfltvfsediqefipyvf
qiiafvveqsatipesikplaqpllapnvwelkgnipavtrllksfiktdssifpdlvpv
lgifqrliaskayevhgfdllehimllidmnrlrpyikqiavlllqrlqnskteryvkkl
tvffglisnklgsdflihfidevqdglfqqiwgnfiittlptignlldrkialigvlnmv
ingqffqskyptlisstmnsiietassianlkndyveeistfgshfsklvsisekpfdpl
peidvnngvrlyvaealnkynaisgntflntilpqltqenqvklnqllvg