PDB entry 1w2d

View 1w2d on RCSB PDB site
Description: Human Inositol (1,4,5)-trisphosphate 3-kinase complexed with Mn2+/ADP/Ins(1,3,4,5)P4
Class: transferase
Keywords: inositol phosphate kinase, ADP, ip4, transferase
Deposited on 2004-07-01, released 2004-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inositol-trisphosphate 3-kinase a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2da_
  • Chain 'B':
    Compound: inositol-trisphosphate 3-kinase a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2db_
  • Heterogens: ADP, 4IP, MN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1w2dA (A:)
    sfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlqdlldgfd
    gpcvldckmgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqravtkprym
    qwregisssttlgfriegikkadgscstdfkttrsreqvlrvfeefvqgdeevlrrylnr
    lqqirdtlevseffrrhevigssllfvhdhchragvwlidfgkttplpdgqildhrrpwe
    egnredgyllgldnligilaslaer
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1w2dB (B:)
    sfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlqdlldgfd
    gpcvldckmgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqravtkprym
    qwregisssttlgfriegikkadgscstdfkttrsreqvlrvfeefvqgdeevlrrylnr
    lqqirdtlevseffrrhevigssllfvhdhchragvwlidfgkttplpdgqildhrrpwe
    egnredgyllgldnligilaslaer
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w2dB (B:)
    sfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlqdlldgfd
    gpcvldckmgvrtyleeeltkaklrkdmykkmlavdpavtkprymqwregisssttlgfr
    iegikkadgscstdfkttrsreqvlrvfeefvqgdeevlrrylnrlqqirdtlevseffr
    rhevigssllfvhdhchragvwlidfgkttplpdgqildhrrpweegnredgyllgldnl
    igilaslaer