PDB entry 1tu0

View 1tu0 on RCSB PDB site
Description: Aspartate Transcarbamoylase Catalytic Chain Mutant E50A Complex with Phosphonoacetamide
Class: hydrolase/hydrolase regulator
Keywords: protein structure-function, site-specific mutagenesis, domain closure, allosteric transition, HYDROLASE-HYDROLASE REGULATOR COMPLEX
Deposited on 2004-06-23, released 2004-07-20
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.211
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aspartate carbamoyltransferase catalytic chain
    Species: Escherichia coli [TaxId:562]
    Gene: PYRB, B4245, C5345, Z5856, ECS5222, SF4245, S4507
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A786 (0-309)
      • engineered (49)
    Domains in SCOPe 2.02: d1tu0a2, d1tu0a3
  • Chain 'B':
    Compound: Aspartate carbamoyltransferase regulatory chain
    Species: Escherichia coli [TaxId:562]
    Gene: PYRI, B4244, C5344, Z5855, ECS5221
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A7F3 (1-152)
      • initiating methionine (0)
    Domains in SCOPe 2.02: d1tu0b1, d1tu0b2
  • Chain 'C':
    Compound: Aspartate carbamoyltransferase catalytic chain
    Species: Escherichia coli [TaxId:562]
    Gene: PYRB, B4245, C5345, Z5856, ECS5222, SF4245, S4507
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A786 (0-309)
      • engineered (49)
    Domains in SCOPe 2.02: d1tu0c2, d1tu0c3
  • Chain 'D':
    Compound: Aspartate carbamoyltransferase regulatory chain
    Species: Escherichia coli [TaxId:562]
    Gene: PYRI, B4244, C5344, Z5855, ECS5221
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A7F3 (1-152)
      • initiating methionine (0)
    Domains in SCOPe 2.02: d1tu0d1, d1tu0d2
  • Heterogens: ZN, PCT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu0A (A:)
anplyqkhiisindlsrddlnlvlataaklkanpqpellkhkviascffaastrtrlsfe
tsmhrlgasvvgfsdsantslgkkgetladtisvistyvdaivmrhpqegaarlatefsg
nvpvlnagdgsnqhptqtlldlftiqetqgrldnlhvamvgdlkygrtvhsltqalakfd
gnrfyfiapdalampqyildmldekgiawslhssieevmaevdilymtrvqkerldpsey
anvkaqfvlrasdlhnakanmkvlhplprvdeiatdvdktphawyfqqagngifarqall
alvlnrdlvl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu0B (B:)
mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
vsssfavrkrandialkckycekefshnvvlan

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu0C (C:)
anplyqkhiisindlsrddlnlvlataaklkanpqpellkhkviascffaastrtrlsfe
tsmhrlgasvvgfsdsantslgkkgetladtisvistyvdaivmrhpqegaarlatefsg
nvpvlnagdgsnqhptqtlldlftiqetqgrldnlhvamvgdlkygrtvhsltqalakfd
gnrfyfiapdalampqyildmldekgiawslhssieevmaevdilymtrvqkerldpsey
anvkaqfvlrasdlhnakanmkvlhplprvdeiatdvdktphawyfqqagngifarqall
alvlnrdlvl

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu0D (D:)
mthdnklqveaikrgtvidhipaqigfkllslfkltetdqritiglnlpsgemgrkdlik
ientflsedqvdqlalyapqatvnridnyevvgksrpslperidnvlvcpnsncishaep
vsssfavrkrandialkckycekefshnvvlan