PDB entry 1tij

View 1tij on RCSB PDB site
Description: 3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets
Class: hydrolase inhibitor
Keywords: human cystatin c dimer, 3d domain swapping, amyloid formation, inhibitor of c1 and c13 cysteine proteases, amyloid angiopathy, cerebral hemorrhage, hydrolase inhibitor
Deposited on 2004-06-02, released 2005-07-19
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.03 Å
R-factor: 0.217
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cystatin C
    Species: Homo sapiens [TaxId:9606]
    Gene: CST3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1tija1
  • Chain 'B':
    Compound: Cystatin C
    Species: Homo sapiens [TaxId:9606]
    Gene: CST3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1tijb1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tijA (A:)
sspgkpprlvggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagv
nyfldvelgrttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda

    Sequence, based on observed residues (ATOM records): (download) 
    >1tijA (A:)
prlvggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldv
elgrttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1tijB (B:)
sspgkpprlvggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagv
nyfldvelgrttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda

    Sequence, based on observed residues (ATOM records): (download) 
    >1tijB (B:)
lvggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvel
grttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda