PDB entry 1tbr

View 1tbr on RCSB PDB site
Description: crystal structure of insect derived double domain kazal inhibitor rhodniin in complex with thrombin
Class: complex (serine protease/inhibitor)
Keywords: COMPLEX (SERINE PROTEASE-INHIBITOR), KAZAL-TYPE INHIBITOR, THROMBIN, COMPLEX (SERINE PROTEASE-INHIBITOR) complex
Deposited on 1995-03-03, released 1996-10-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.189
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1tbr.1
  • Chain 'J':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1tbr.2
  • Chain 'K':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1tbr.2
  • Chain 'L':
    Compound: thrombin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1tbr.1
  • Chain 'R':
    Compound: rhodniin
    Species: Rhodnius prolixus [TaxId:13249]
    Gene: PRPTI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1tbrr1, d1tbrr2
  • Chain 'S':
    Compound: rhodniin
    Species: Rhodnius prolixus [TaxId:13249]
    Gene: PRPTI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1tbrs1, d1tbrs2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tbrH (H:)
ivegqdaevglspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftvddll
vrigkhsrtryerkvekismldkiyihprynwkenldrdiallklkrpielsdyihpvcl
pdkqtaakllhagfkgrvtgwgnrretwttsvaevqpsvlqvvnlplverpvckastrir
itdnmfcagykpgegkrgdacegdsggpfvmkspynnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidrlgs

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tbrJ (J:)
tsedhfqpffnektfgageadcglrplfekkqvqdqtekelfesyiegr

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tbrK (K:)
ivegqdaevglspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftvddll
vrigkhsrtryerkvekismldkiyihprynwkenldrdiallklkrpielsdyihpvcl
pdkqtaakllhagfkgrvtgwgnrretwttsvaevqpsvlqvvnlplverpvckastrir
itdnmfcagykpgegkrgdacegdsggpfvmkspynnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidrlgs

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tbrL (L:)
tsedhfqpffnektfgageadcglrplfekkqvqdqtekelfesyiegr

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tbrR (R:)
eggepcacphalhrvcgsdgetysnpctlncakfngkpelvkvhdgpcepdededvcqec
dgdeykpvcgsdditydnncrlecasissspgvelkhegpcrt

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tbrS (S:)
eggepcacphalhrvcgsdgetysnpctlncakfngkpelvkvhdgpcepdededvcqec
dgdeykpvcgsdditydnncrlecasissspgvelkhegpcrt