PDB entry 1t5x
View 1t5x on RCSB PDB site
Description: HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2
Class: immune system
Keywords: MHC class II; major histocompatibiloty complex protein; HLA-DR1; superantigen; antigen; peptide, IMMUNE SYSTEM
Deposited on
2004-05-05, released
2004-08-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hla class II histocompatibility antigen, dr alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DRA*0101
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1t5xa1, d1t5xa2 - Chain 'B':
Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DRB1*0101
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1t5xb1, d1t5xb2 - Chain 'C':
Compound: 15-mer peptide fragment of Regulatory protein MIG1
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: Enterotoxin type C-3
Species: Staphylococcus aureus [TaxId:1280]
Gene: SEC3
Database cross-references and differences (RAF-indexed):
- Uniprot P0A0L5 (0-238)
- engineered (42)
- engineered (44-46)
Domains in SCOPe 2.08: d1t5xd1, d1t5xd2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1t5xA (A:)
keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
a
Sequence, based on observed residues (ATOM records): (download)
>1t5xA (A:)
ehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalani
avdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwlr
ngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefda
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1t5xB (B:)
gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewra
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence, based on SEQRES records: (download)
>1t5xD (D:)
esqpdpmpddlhksseftgtmgnmkylyddhyvsatkvksvdsffkwdliynisdkklkn
ydkvktellnedlakkykdevvdvygsnyyvncyfsskdnvgkvtggktcmyggitkheg
nhfdngnlqnvlvrvyenkrntisfevqtdkksvtaqeldikarnflinkknlyefnssp
yetgyikfienngntfwydmmpapgdkfdqskylmmyndnktvdsksvkievhlttkng
Sequence, based on observed residues (ATOM records): (download)
>1t5xD (D:)
esqpdpmpddlhksseftgtmgnmkylyddhyvsatkvksvdsffkwdliynisdkklkn
ydkvktellnedlakkykdevvdvygsnyyvncyfsggktcmyggitkhegnhfdngnlq
nvlvrvyenkrntisfevqtdkksvtaqeldikarnflinkknlyefnsspyetgyikfi
enngntfwydmmpapgdkfdqskylmmyndnktvdsksvkievhlttkng