PDB entry 1t4e
View 1t4e on RCSB PDB site
Description: Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor
Class: ligase
Keywords: MDM2-Inhibitor complex
Deposited on
2004-04-29, released
2005-02-08
The last revision prior to the SCOP 1.73 freeze date was dated
2005-04-12, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.239
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: ubiquitin-protein ligase e3 mdm2
Species: HOMO SAPIENS
Gene: MDM2
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1t4ea1 - Chain 'B':
Compound: ubiquitin-protein ligase e3 mdm2
Species: HOMO SAPIENS
Gene: MDM2
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1t4eb1 - Heterogens: DIZ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1t4eA (A:)
gsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhiv
ycsndllgdlfgvpsfsvkehrkiytmiyrnlvvvn
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1t4eB (B:)
gsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhiv
ycsndllgdlfgvpsfsvkehrkiytmiyrnlvvvn