PDB entry 1t44

View 1t44 on RCSB PDB site
Description: Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation
Class: structural protein
Keywords: structural protein
Deposited on 2004-04-28, released 2004-09-07
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.147
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1t44a1, d1t44a2
  • Chain 'G':
    Compound: Chimera of Gelsolin domain 1 and C-Terminal domain of thymosin Beta-4
    Species: Homo sapiens, Mus musculus [TaxId:9606,10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1t44g_
  • Heterogens: CA, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t44A (A:)
talvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfe
tfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdl
tdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdg
qvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydea
gpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >1t44A (A:)
talvcdngsglvkagfagddapravfpsivgrpdsyvgdeaqskrgiltlkypiehgiit
nwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyvaiq
avlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilterg
ysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerfrc
petlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqkei
talapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkcf

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1t44G (G:)
gshehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
vasgfkhvetqeknplpsketieqekq

    Sequence, based on observed residues (ATOM records): (download) 
    >1t44G (G:)
ehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlhy
wlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggvas
gfkhvetqeknplpsketieqekq