PDB entry 1svs

View 1svs on RCSB PDB site
Description: Structure of the K180P mutant of Gi alpha subunit bound to GppNHp.
Class: hydrolase, signaling protein
Keywords: Gi alpha subunit, K180P mutation, GppNHp (GNP) bound, HYDROLASE, SIGNALING PROTEIN
Deposited on 2004-03-29, released 2004-06-01
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.2
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Guanine nucleotide-binding protein G(i), alpha-1 subunit
    Species: Rattus norvegicus [TaxId:10116]
    Gene: GNAI1, GNAI-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10824
      • engineered (178)
    Domains in SCOPe 2.04: d1svsa1
  • Heterogens: MG, GNP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1svsA (A:)
gctlsaedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagy
seeeckqykavvysntiqsiiaiiramgrlkidfgdaaraddarqlfvlagaaeegfmta
elagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvpt
tgivethftfkdlhfkmfdvggqrserkkwihcfegvtaiifcvalsdydlvlaedeemn
rmhesmklfdsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaa
yiqcqfedlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >1svsA (A:)
revkllllgagesgkstivkqmkiiheagyseeeckqykavvysntiqsiiaiiramgrl
kidfgdaaraddarqlfvlagaaeegfmtaelagvikrlwkdsgvqacfnrsreyqlnds
aayylndldriaqpnyiptqqdvlrtrvpttgivethftfkdlhfkmfdvggqrserkkw
ihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkk
dlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcatdtkn
vqfvfdavtdviiknn