PDB entry 1s5e

View 1s5e on RCSB PDB site
Description: Cholera holotoxin, Crystal form 1
Class: transferase,toxin
Keywords: cholera toxin, heat-labile enterotoxin, ADP ribose transferases, AB5 toxins, TRANSFERASE,TOXIN
Deposited on 2004-01-20, released 2004-04-06
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.169
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cholera enterotoxin, A chain precursor
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXA, TOXA, VC1457
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5ea_
  • Chain 'B':
    Compound: Cholera enterotoxin, A chain precursor
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXA, TOXA, VC1457
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5eb_
  • Chain 'D':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5ed_
  • Chain 'E':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5ee_
  • Chain 'F':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5ef_
  • Chain 'G':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5eg_
  • Chain 'H':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5eh_
  • Chain 'J':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5ej_
  • Chain 'K':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5ek_
  • Chain 'L':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5el_
  • Chain 'M':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5em_
  • Chain 'N':
    Compound: cholera toxin B protein (CTB)
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1s5en_
  • Heterogens: GAL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s5eA (A:)
nddklyradsrppdeikqsgglmprgqseyfdrgtqmninlydhargtqtgfvrhddgyv
stsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpdeqevsalggip
ysqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwi
hhappgcgnaprssmsntcdektqslgvkfldeyqskvkrqifsgyqsdidthnrikdel

    Sequence, based on observed residues (ATOM records): (download) 
    >1s5eA (A:)
nddklyradsrppdeikqsgglmprgqseyfdrgtqmninlydhargtqgfvrhddgyvs
tsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpdeqevsalggipy
sqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwih
happgcgnaprsntcdektqslgvkfldeyqskvkrqifsgyqsdidthnri

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s5eB (B:)
nddklyradsrppdeikqsgglmprgqseyfdrgtqmninlydhargtqtgfvrhddgyv
stsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpdeqevsalggip
ysqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwi
hhappgcgnaprssmsntcdektqslgvkfldeyqskvkrqifsgyqsdidthnrikdel

    Sequence, based on observed residues (ATOM records): (download) 
    >1s5eB (B:)
nddklyradsrppdeikqsgglmprgqseyfdrgtqmninlydhargtqtgfvrhddgyv
stsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpdeqevsalggip
ysqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwi
hhappgcgntcdektqslgvkfldeyqskvkrqifsgyqsdidthnr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eD (D:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eE (E:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eF (F:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1s5eG (G:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >1s5eG (G:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisma

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eH (H:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eJ (J:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eK (K:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eL (L:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eM (M:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5eN (N:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman