PDB entry 1pvr

View 1pvr on RCSB PDB site
Description: basis for a switch in substrate specificity: crystal structure of selected variant of cre site-specific recombinase, lnsgg bound to the loxp (wildtype) recognition site
Class: recombination/DNA
Keywords: CRE, Recombinase, DNA, CRE-LOXP RECOMBINATION, RECOMBINATION/DNA COMPLEX
Deposited on 2003-06-28, released 2004-02-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.212
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Recombinase cre
    Species: Enterobacteria phage P1 [TaxId:10678]
    Gene: cre
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06956
      • engineered (179)
      • engineered (263-264)
      • engineered (267)
      • engineered (271)
    Domains in SCOPe 2.05: d1pvra1, d1pvra2
  • Chain 'B':
    Compound: Recombinase cre
    Species: Enterobacteria phage P1 [TaxId:10678]
    Gene: cre
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06956
      • engineered (179)
      • engineered (263-264)
      • engineered (267)
      • engineered (271)
    Domains in SCOPe 2.05: d1pvrb1, d1pvrb2
  • Chain 'C':
    Compound: 34-mer
  • Chain 'D':
    Compound: 34-mer
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pvrA (A:)
mhhhhhhsnlltvhqnlpalpvdatsdevrknlmdmfrdrqafsehtwkmllsvcrswaa
wcklnnrkwfpaepedvrdyllylqarglavktiqqhlgqlnmlhrrsglprpsdsnavs
lvmrrirkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllrl
aeiarirvkdisrtdggrmlihigrtktlvstagvekalslgvtklverwisvsgvaddp
nnylfcrvrkngvaapsatsqlsnsalggifgathrliygakddsgqrylawsghsarvg
aardmaragvsipeimqaggwtnvnivmnyirnldsetgamvrlledgd

    Sequence, based on observed residues (ATOM records): (download) 
    >1pvrA (A:)
atsdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnnrkwfpaepedvrdylly
lqarglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalaf
ertdfdqvrslmensdrcqdirnlaflgiayntllrlaeiarirvkdisrtdggrmlihi
grtktlvstagvekalslgvtklverwisvsgvaddpnnylfcrvrkngvaapsatsqls
nsalggifgathrliygakddsgqrylawsghsarvgaardmaragvsipeimqaggwtn
vnivmnyirnldsetgamvrlled

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pvrB (B:)
mhhhhhhsnlltvhqnlpalpvdatsdevrknlmdmfrdrqafsehtwkmllsvcrswaa
wcklnnrkwfpaepedvrdyllylqarglavktiqqhlgqlnmlhrrsglprpsdsnavs
lvmrrirkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllrl
aeiarirvkdisrtdggrmlihigrtktlvstagvekalslgvtklverwisvsgvaddp
nnylfcrvrkngvaapsatsqlsnsalggifgathrliygakddsgqrylawsghsarvg
aardmaragvsipeimqaggwtnvnivmnyirnldsetgamvrlledgd

    Sequence, based on observed residues (ATOM records): (download) 
    >1pvrB (B:)
tsdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnnrkwfpaepedvrdyllyl
qarglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafe
rtdfdqvrslmensdrcqdirnlaflgiayntllrlaeiarirvkdisrtdggrmlihig
rtktlvstagvekalslgvtklverwisvsgvaddpnnylfcrvrkngvaapsatsqlsn
salggifgathrliygakddsgqrylawsghsarvgaardmaragvsipeimqaggwtnv
nivmnyirnltgamvrlled

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.