PDB entry 1pq2

View 1pq2 on RCSB PDB site
Description: Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Class: oxidoreductase
Keywords: cytochrome p450, cyp2c8, membrane protein, taxol 6-hydroxylase, oxidoreductase
Deposited on 2003-06-17, released 2004-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.248
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2C8
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2C8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1pq2a_
  • Chain 'B':
    Compound: Cytochrome P450 2C8
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2C8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1pq2b_
  • Heterogens: PO4, HEM, PLM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pq2A (A:)
makktsskgklppgptplpiignmlqidvkdicksftnfskvygpvftvyfgmnpivvfh
gyeavkealidngeefsgrgnspisqritkglgiissngkrwkeirrfslttlrnfgmgk
rsiedrvqeeahclveelrktkaspcdptfilgcapcnvicsvvfqkrfdykdqnfltlm
krfnenfrilnspwiqvcnnfpllidcfpgthnkvlknvaltrsyirekvkehqasldvn
nprdfidcflikmeqekdnqksefnienlvgtvadlfvagtettsttlryglllllkhpe
vtakvqeeidhvigrhrspcmqdrshmpytdavvheiqrysdlvptgvphavttdtkfrn
ylipkgttimalltsvlhddkefpnpnifdpghfldkngnfkksdyfmpfsagkricage
glarmelflflttilqnfnlksvddlknlnttavtkgivslppsyqicfipvhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pq2A (A:)
klppgptplpiignmlqidvkdicksftnfskvygpvftvyfgmnpivvfhgyeavkeal
idngeefsgrgnspisqritkglgiissngkrwkeirrfslttlrnfgmgkrsiedrvqe
eahclveelrktkaspcdptfilgcapcnvicsvvfqkrfdykdqnfltlmkrfnenfri
lnspwiqvcnnfpllidcfpgthnkvlknvaltrsyirekvkehqasldvnnprdfidcf
likmeqekdnqksefnienlvgtvadlfvagtettsttlryglllllkhpevtakvqeei
dhvigrhrspcmqdrshmpytdavvheiqrysdlvptgvphavttdtkfrnylipkgtti
malltsvlhddkefpnpnifdpghfldkngnfkksdyfmpfsagkricageglarmelfl
flttilqnfnlksvddlknlnttavtkgivslppsyqicfipv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pq2B (B:)
makktsskgklppgptplpiignmlqidvkdicksftnfskvygpvftvyfgmnpivvfh
gyeavkealidngeefsgrgnspisqritkglgiissngkrwkeirrfslttlrnfgmgk
rsiedrvqeeahclveelrktkaspcdptfilgcapcnvicsvvfqkrfdykdqnfltlm
krfnenfrilnspwiqvcnnfpllidcfpgthnkvlknvaltrsyirekvkehqasldvn
nprdfidcflikmeqekdnqksefnienlvgtvadlfvagtettsttlryglllllkhpe
vtakvqeeidhvigrhrspcmqdrshmpytdavvheiqrysdlvptgvphavttdtkfrn
ylipkgttimalltsvlhddkefpnpnifdpghfldkngnfkksdyfmpfsagkricage
glarmelflflttilqnfnlksvddlknlnttavtkgivslppsyqicfipvhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pq2B (B:)
klppgptplpiignmlqidvkdicksftnfskvygpvftvyfgmnpivvfhgyeavkeal
idngeefsgrgnspisqritkglgiissngkrwkeirrfslttlrnfgmgkrsiedrvqe
eahclveelrktkaspcdptfilgcapcnvicsvvfqkrfdykdqnfltlmkrfnenfri
lnspwiqvcnnfpllidcfpgthnkvlknvaltrsyirekvkehqasldvnnprdfidcf
likmeqekdnqksefnienlvgtvadlfvagtettsttlryglllllkhpevtakvqeei
dhvigrhrspcmqdrshmpytdavvheiqrysdlvptgvphavttdtkfrnylipkgtti
malltsvlhddkefpnpnifdpghfldkngnfkksdyfmpfsagkricageglarmelfl
flttilqnfnlksvddlknlnttavtkgivslppsyqicfipv