PDB entry 1p1u

View 1p1u on RCSB PDB site
Description: Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form)
Class: membrane protein
Keywords: ionotropic glutamate receptor, AMPA receptor, ion channel, ligand-binding domain, MEMBRANE PROTEIN
Deposited on 2003-04-14, released 2003-06-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: GRIA2 OR GLUR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (119-End)
      • linker (117-118)
      • engineered (137)
    Domains in SCOPe 2.07: d1p1ua_
  • Chain 'B':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: GRIA2 OR GLUR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (119-End)
      • linker (117-118)
      • engineered (137)
    Domains in SCOPe 2.07: d1p1ub_
  • Heterogens: SO4, AMQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1p1uA (A:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlk
lneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >1p1uA (A:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1p1uB (B:)
ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
iesaedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
vrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlk
lneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >1p1uB (B:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygttdsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec