PDB entry 1oku
View 1oku on RCSB PDB site
Description: cyclin a binding groove inhibitor h-ala-ala-abu-arg-er-leu-ile-(p-f-phe)-nh2
Class: complex(kinase/cyclin)
Keywords: cyclin a, ligand exchange, drug design, peptidomimetics
Deposited on
2003-07-30, released
2003-12-11
The last revision prior to the SCOPe 2.06 freeze date was dated
2003-12-11, with a file datestamp of
2007-06-28.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.209
AEROSPACI score: 0.22
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1okua_ - Chain 'B':
Compound: cyclin a2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: Cell division protein kinase 2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1okuc_ - Chain 'D':
Compound: cyclin a2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
- Chain 'F':
Compound: ala-ala-aba-arg-ser-leu-ile-pff-nh2
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: ala-ala-aba-arg-ser-leu-ile-pff-nh2
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1okuA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>1okuA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1okuC (C:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>1okuC (C:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'D':
No sequence available.
- Chain 'F':
No sequence available.
- Chain 'H':
No sequence available.