PDB entry 1nh0

View 1nh0 on RCSB PDB site
Description: 1.03 A structure of HIV-1 protease: inhibitor binding inside and outside the active site
Class: hydrolase/hydrolase inhibitor
Keywords: aspartyl protease, human immunodeficiency virus, inhibitor design, hydrolase-hydrolase inhibitor complex
Deposited on 2002-12-18, released 2004-04-13
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.03 Å
R-factor: 0.131
AEROSPACI score: 0.98 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: protease retropepsin
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
  Domains in SCOPe 2.04: d1nh0a_
• Chain 'B':
  Compound: protease retropepsin
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
  Domains in SCOPe 2.04: d1nh0b_
• Chain 'I':
  Compound: peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
  Database cross-references and differences (RAF-indexed):
  • PDB 1NH0 (0-End)
• Chain 'J':
  Compound: peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
  Database cross-references and differences (RAF-indexed):
  • PDB 1NH0 (0-End)
• Heterogens: SO4, BME, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1nh0A (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1nh0B (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  No sequence available.