PDB entry 1n2b

View 1n2b on RCSB PDB site
Description: Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP and pantoate, higher occupancy of pantoate and lower occupancy of AMPCPP in subunit A
Class: ligase
Keywords: Rossmann fold, dimer, intersubunit beta sheet, structural genomics, PSI, Protein Structure Initiative, TB Structural Genomics Consortium, TBSGC, LIGASE
Deposited on 2002-10-22, released 2003-04-22
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.184
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pantothenate synthetase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: panC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A5R0
      • engineered (76)
    Domains in SCOPe 2.04: d1n2ba_
  • Chain 'B':
    Compound: Pantothenate synthetase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: panC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A5R0
      • engineered (1)
    Domains in SCOPe 2.04: d1n2bb_
  • Heterogens: MG, SO4, APC, PAF, GOL, EOH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1n2bA (A:)
maipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgs
vvvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqp
gplaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldva
vvgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravld
aapgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigtfagtdrpdgyr

    Sequence, based on observed residues (ATOM records): (download) 
    >1n2bA (A:)
ipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsvv
vvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqpgp
laaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavv
gvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaa
pgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieig

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1n2bB (B:)
maipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgs
vvvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqp
gplaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldva
vvgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravld
aapgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigtfagtdrpdgyr

    Sequence, based on observed residues (ATOM records): (download) 
    >1n2bB (B:)
aipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsv
vvvsifvnpmqfgayprtpdddlaqlraegveiaftpttaamypdglrttvqpgplaael
eggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvgvptv
readglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaapgvav
dylelrdiglgpmplngsgrllvaarlgttrlldniaieig