PDB entry 1mq8
View 1mq8 on RCSB PDB site
Description: Crystal structure of alphaL I domain in complex with ICAM-1
Class: immune system
Keywords: Ig superfamily, Rossmann fold, metal mediated protein interface, IMMUNE SYSTEM
Deposited on
2002-09-15, released
2003-01-14
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.264
AEROSPACI score: 0.1
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: intercellular adhesion molecule-1
Species: Homo sapiens [TaxId:9606]
Gene: ICAM-1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1mq8a1, d1mq8a2 - Chain 'B':
Compound: Integrin alpha-L
Species: Homo sapiens [TaxId:9606]
Gene: LFA-1 (AlphaLbeta2)
Database cross-references and differences (RAF-indexed):
- Uniprot P20701 (0-176)
- engineered (31)
- engineered (169)
Domains in SCOPe 2.02: d1mq8b_ - Chain 'C':
Compound: intercellular adhesion molecule-1
Species: Homo sapiens [TaxId:9606]
Gene: ICAM-1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1mq8c1, d1mq8c2 - Chain 'D':
Compound: Integrin alpha-L
Species: Homo sapiens [TaxId:9606]
Gene: LFA-1 (AlphaLbeta2)
Database cross-references and differences (RAF-indexed):
- Uniprot P20701 (0-176)
- engineered (31)
- engineered (169)
Domains in SCOPe 2.02: d1mq8d_ - Heterogens: NAG, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1mq8A (A:)
qtsvspskvilprggsvlvtcstscdqpkllgietplpkkelllpgnnrkvyelsnvqed
sqpmcysncpdgqstaktfltvywtpervelaplpswqpvgknltlrcqveggapranlt
vvllrgekelkrepavgepaevtttvlvrrdhhganfscrteldlrpqglelfentsapy
qlqtfvlpatppqlvsprvlevdtqgtvvcsldglfpvseaqvhlalgdqrlnptvtygn
dsfsakasvsvtaedegtqrltcavilgnqsqetlqtvtiysfpapnvilt
Sequence, based on observed residues (ATOM records): (download)
>1mq8A (A:)
qtsvspskvilprggsvlvtcstscdqpkllgietplpkkelllpgnnrkvyelsnvqed
sqpmcysncpdgqstaktfltvywtpervelaplpswqpvgknltlrcqveggapranlt
vvllrgekelkrepavgepaevtttvlvrrdhhganfscrteldlrpqglelfentsapy
qlqt
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1mq8B (B:)
vdlvflfdgsmslqpdefqkildfmkdvmkkcsntsyqfaavqfstsyktefdfsdyvkr
kdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatdsgnid
aakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlctelqkki
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1mq8C (C:)
qtsvspskvilprggsvlvtcstscdqpkllgietplpkkelllpgnnrkvyelsnvqed
sqpmcysncpdgqstaktfltvywtpervelaplpswqpvgknltlrcqveggapranlt
vvllrgekelkrepavgepaevtttvlvrrdhhganfscrteldlrpqglelfentsapy
qlqtfvlpatppqlvsprvlevdtqgtvvcsldglfpvseaqvhlalgdqrlnptvtygn
dsfsakasvsvtaedegtqrltcavilgnqsqetlqtvtiysfpapnvilt
Sequence, based on observed residues (ATOM records): (download)
>1mq8C (C:)
qtsvspskvilprggsvlvtcstscdqpkllgietplpkkelllpgnnrkvyelsnvqed
sqpmcysncpdgqstaktfltvywtpervelaplpswqpvgknltlrcqveggapranlt
vvllrgekelkrepavgepaevtttvlvrrdhhganfscrteldlrpqglelfentsapy
qlqt
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1mq8D (D:)
vdlvflfdgsmslqpdefqkildfmkdvmkkcsntsyqfaavqfstsyktefdfsdyvkr
kdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatdsgnid
aakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlctelqkki